Tbio ZBTB21 Zinc finger and BTB domain-containing protein 21

Protein Summary

Description

Acts as a transcription repressor.

Uniprot Accession IDs

• Q9ULJ3
• Q5R2W1
• Q5R2W2
• Q6P4R0

Gene Name

• ZBTB21

Ensembl ID

• ENST00000310826
• ENSP00000308759
• ENSG00000173276
• ENST00000398499
• ENSP00000381512
• ENST00000398505
• ENSP00000381517
• ENST00000398511
• ENSP00000381523

Symbol

• KIAA1227
• ZNF295
• ZNF295

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
cell type or tissue	0.97
microRNA	0.88
protein domain	0.85
transcription factor binding site profile	0.82
histone modification site profile	0.8

Protein Classes

PANTHER Classes

Protein / Transcription Factor / Zinc Finger Transcription Factor / Zinc Finger And Btb Domain-containing Protein 21

Protein / ... / Krab Box Transcription Factor / Zinc Finger And Btb Domain-containing Protein 21

DTO Classes

Protein / Transcription Factor / Zinc Finger Transcription Factor / C2h2 Zinc Finger Transcription Factor / Krab Box Transcription Factor / Zinc Finger And Btb Domain-containing Protein 21

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 7.51   (req: < 5)

Gene RIFs: 3   (req: <= 3)

Antibodies: 78   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 7.51   (req: >= 5)

Gene RIFs: 3   (req: > 3)

Antibodies: 78   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0