Tbio WWC3 Protein WWC3

Protein Summary

Description

This gene encodes a member of the WWC family of proteins, which also includes the WWC1 (KIBRA) gene product and the WWC2 gene product. The protein encoded by this gene includes a C2 domain, which is known to mediate homodimerization in the related WWC1 gene product. [provided by RefSeq, Sep 2011]

Uniprot Accession IDs

• Q9ULE0
• A8KA96
• Q659C1
• Q9BTQ1

Gene Name

• WWC3

Ensembl ID

• ENST00000380861
• ENSP00000370242
• ENSG00000047644

Symbol

• KIAA1280
• BM042

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
tissue sample	0.64
cell line	0.63
cell type or tissue	0.61
microRNA	0.58
phenotype	0.51

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 12.14   (req: < 5)

Gene RIFs: 2   (req: <= 3)

Antibodies: 71   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 12.14   (req: >= 5)

Gene RIFs: 2   (req: > 3)

Antibodies: 71   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0