BRPF3
Bromodomain and PHD finger-containing protein 3
Protein Summary
Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity.
- ENST00000339717
- ENSP00000345419
- ENSG00000096070
- ENST00000357641
- ENSP00000350267
- ENST00000534694
- ENSP00000434501
- KIAA1286
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
protein domain | 0.99 | ||
transcription factor binding site profile | 0.78 | ||
histone modification site profile | 0.75 | ||
tissue sample | 0.67 | ||
microRNA | 0.64 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 6.47 (req: < 5)
Gene RIFs: 0 (req: <= 3)
Antibodies: 76 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 6.47 (req: >= 5)
Gene RIFs: 0 (req: > 3)
Antibodies: 76 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 3
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligands: 11
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0
Expression Data (0 Tissues)
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
Active Ligands (11)
Protein-Protein Interactions (54)
Nearest Tclin Targets
Pathways (13)
Reactome (13)
Click on a row in the table to change the structure displayed.
Data Source | Name | Explore in Pharos | Explore in Source | ||
|---|---|---|---|---|---|
Reactome | Chromatin modifying enzymes | ||||
Reactome | Chromatin organization | ||||
Reactome | Gene expression (Transcription) | ||||
Reactome | Generic Transcription Pathway | ||||
Reactome | HATs acetylate histones | ||||
Name | Explore in Pharos | Explore in Source | ||
|---|---|---|---|---|
Chromatin modifying enzymes | ||||
Chromatin organization | ||||
Gene expression (Transcription) | ||||
Generic Transcription Pathway | ||||
HATs acetylate histones | ||||
Viral Interactions (0)
Gene Ontology Terms (6)
Functions (1)
Components (3)
Processes (2)
GO Term | Evidence | Assigned by | ||
|---|---|---|---|---|
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
Disease Associations (null)
GWAS Traits (7)
Items per page:
1 – 5 of 7
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
|---|---|---|---|---|---|---|---|---|---|
blood protein measurement | 1 | 1 | 1 | 51 | |||||
hemoglobin measurement | 1 | 1 | 1 | 11 | |||||
hematocrit | 1 | 1 | 1 | 9 | |||||
1 | 1 | 1 | 4.9 | ||||||
substance abuse | 1 | 1 | 1 | 4.9 | |||||
Items per page:
1 – 5 of 7
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
|---|---|---|---|---|---|---|---|
blood protein measurement | 1 | 51 | |||||
hemoglobin measurement | 1 | 11 | |||||
hematocrit | 1 | 9 | |||||
1 | 4.9 | ||||||
substance abuse | 1 | 4.9 | |||||
Find similar targets by:
IDG Resources
Orthologs (10)
1 – 5 of 10
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
|---|---|---|---|---|---|---|---|---|
Chimp | bromodomain and PHD finger containing 3 | VGNC:2650 | 462645 | |||||
Macaque | bromodomain and PHD finger containing 3 | 718997 | ||||||
Mouse | MGI:2146836 | 268936 | ||||||
Rat | RGD:1306868 | 309647 | ||||||
Dog | bromodomain and PHD finger containing 3 | VGNC:38534 | 481762 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
|---|---|---|---|---|---|---|
Chimp | bromodomain and PHD finger containing 3 | |||||
Macaque | bromodomain and PHD finger containing 3 | |||||
Mouse | ||||||
Rat | ||||||
Dog | bromodomain and PHD finger containing 3 | |||||
Publication Statistics
PubMed Score 6.47
PubMed score by year
PubTator Score 0.77
PubTator score by year
Related Publications
Text Mined References (8)
Items per page:
0 of 0
PMID | Year | Title |
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