Protein Summary
Endothelial sialomucin, also called endomucin or mucin-like sialoglycoprotein, which interferes with the assembly of focal adhesion complexes and inhibits interaction between cells and the extracellular matrix. EMCN is a mucin-like sialoglycoprotein that interferes with the assembly of focal adhesion complexes and inhibits interaction between cells and the extracellular matrix (Kinoshita et al., 2001 [PubMed 11418125]).[supplied by OMIM, Mar 2008]
- ENST00000296420
- ENSP00000296420
- ENSG00000164035
- ENST00000305864
- ENSP00000304780
- ENST00000511970
- ENSP00000422432
- EMCN2
- MUC14
- EMCN2
- MUC14
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
gene perturbation | 0.85 | ||
tissue sample | 0.69 | ||
PubMedID | 0.63 | ||
cell type or tissue | 0.58 | ||
disease perturbation | 0.56 | ||
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 24.16 (req: < 5)
Gene RIFs: 5 (req: <= 3)
Antibodies: 188 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 24.16 (req: >= 5)
Gene RIFs: 5 (req: > 3)
Antibodies: 188 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Term: 0
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0
Gene Ontology Terms (3)
Components (3)
Items per page:
10
1 – 3 of 3
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Electronic Annotation (IEA) | UniProtKB-SubCell | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-SubCell | |||
Protein-Protein Interactions (41)
1 – 10 of 41
OSGEP
Family: Enzyme
Novelty: 0.01348632
Score: 0.937
Data Source: STRINGDB
SELL
Novelty: 0.00035489
Score: 0.712
Data Source: STRINGDB
NTAN1
Family: Enzyme
Novelty: 0.00549432
Score: 0.696
Data Source: STRINGDB
PECAM1
Novelty: 0.00020273
Score: 0.696
Data Source: STRINGDB
ADGRL4
Family: GPCR
Novelty: 0.00456769
Score: 0.688
Data Source: STRINGDB
MYCT1
Novelty: 0.07073512
Score: 0.625
Data Source: STRINGDB
CDH5
Novelty: 0.00096405
Score: 0.606
Data Source: STRINGDB
OCIAD2
Novelty: 0.23622047
Score: 0.592
Data Source: STRINGDB
SYNPO2
Novelty: 0.03724055
Score: 0.579
Data Source: STRINGDB
CD300LG
Novelty: 0.12059672
Score: 0.576
Data Source: STRINGDB
Publication Statistics
PubMed Score 24.16
PubMed score by year
PubTator Score 11.34
PubTator score by year
Amino Acid Sequence
Residue Counts
Sequence
MELLQVTILFLLPSICSSNSTGVLEAANNSLVVTTTKPSITTPNTESLQKNVVTPTTGTTPKGTITNELL
1-70
KMSLMSTATFLTSKDEGLKATTTDVRKNDSIISNVTVTSVTLPNAVSTLQSSKPKTETQSSIKTTEIPGS
70-140
VLQPDASPSKTGTLTSIPVTIPENTSQSQVIGTEGGKNASTSATSRSYSSIILPVVIALIVITLSVFVLV
140-210
GLYRMCWKADPGTPENGNDQPQSDKESVKLLTVKTISHESGEHSAQGKTKN
210-261
MELLQVTILFLLPSICSSNSTGVLEAANNSLVVTTTKPSITTPNTESLQKNVVTPTTGTTPKGTITNELLKMSLMSTATFLTSKDEGLKATTTDVRKNDSIISNVTVTSVTLPNAVSTLQSSKPKTETQSSIKTTEIPGSVLQPDASPSKTGTLTSIPVTIPENTSQSQVIGTEGGKNASTSATSRSYSSIILPVVIALIVITLSVFVLVGLYRMCWKADPGTPENGNDQPQSDKESVKLLTVKTISHESGEHSAQGKTKN
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