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Tbio
PCOLCE2
Procollagen C-endopeptidase enhancer 2

Protein Summary
Description
Binds to the C-terminal propeptide of types I and II procollagens and may enhance the cleavage of that propeptide by BMP1.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000295992
  • ENSP00000295992
  • ENSG00000163710

Symbol
  • PCPE2
  • PCPE2
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
PubMedID
0.84
gene perturbation
0.83
histone modification site profile
0.75
transcription factor perturbation
0.68
kinase perturbation
0.66


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 13.42   (req: < 5)
Gene RIFs: 4   (req: <= 3)
Antibodies: 146   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 13.42   (req: >= 5)
Gene RIFs: 4   (req: > 3)
Antibodies: 146   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0