ACIN1
Apoptotic chromatin condensation inducer in the nucleus
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
drug perturbation | 0.99 | ||
interacting protein | 0.94 | ||
disease perturbation | 0.93 | ||
transcription factor binding site profile | 0.87 | ||
ligand (protein) perturbation | 0.83 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
Click on a row in the table to change the structure displayed.
Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Apoptosis | ||||
Reactome | Apoptotic cleavage of cellular proteins | ||||
Reactome | Apoptotic execution phase | ||||
Reactome | Programmed Cell Death | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Apoptosis | ||||
Apoptotic cleavage of cellular proteins | ||||
Apoptotic execution phase | ||||
Programmed Cell Death | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from High Throughput Direct Assay (HDA) | UniProtKB | |||
Non-traceable Author Statement (NAS) | UniProtKB | |||
Non-traceable Author Statement (NAS) | UniProtKB | |||
Non-traceable Author Statement (NAS) | UniProtKB | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
red blood cell distribution width | 6 | 6 | 10 | 99.4 | |||||
eosinophil count | 3 | 5 | 7 | 98 | |||||
basophil count | 5 | 7 | 9 | 98 | |||||
eosinophil percentage of leukocytes | 2 | 7 | 9 | 97 | |||||
reticulocyte count | 6 | 3 | 6 | 97 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
red blood cell distribution width | 10 | 99.4 | |||||
eosinophil count | 7 | 98 | |||||
basophil count | 9 | 98 | |||||
eosinophil percentage of leukocytes | 9 | 97 | |||||
reticulocyte count | 6 | 97 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | apoptotic chromatin condensation inducer 1 | VGNC:3510 | 452792 | |||||
Macaque | apoptotic chromatin condensation inducer 1 | 713310 | ||||||
Mouse | MGI:1891824 | 56215 | ||||||
Rat | RGD:1311945 | 305884 | ||||||
Dog | apoptotic chromatin condensation inducer 1 | VGNC:37507 | 480247 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | apoptotic chromatin condensation inducer 1 | |||||
Macaque | apoptotic chromatin condensation inducer 1 | |||||
Mouse | ||||||
Rat | ||||||
Dog | apoptotic chromatin condensation inducer 1 | |||||
PMID | Year | Title |
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