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Tbio
ADAM29
Disintegrin and metalloproteinase domain-containing protein 29

Protein Summary
Description
May be involved in spermatogenesis and fertilization. Seems to be a non catalytic metalloprotease-like protein. This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene is highly expressed in testis and may be involved in human spermatogenesis. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Jul 2008]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000359240
  • ENSP00000352177
  • ENSG00000168594
  • ENST00000404450
  • ENSP00000384229
  • ENST00000445694
  • ENSP00000414544
  • ENST00000514159
  • ENSP00000423517
  • ENST00000615367
  • ENSP00000484862
  • ENST00000618444
  • ENSP00000478469

Symbol
  • CT73
  • svph1
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
protein domain
0.85
cell type or tissue
0.63
virus perturbation
0.59
kinase perturbation
0.54
molecular function
0.49


Protein Classes
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 14   (req: < 5)
Gene RIFs: 5   (req: <= 3)
Antibodies: 78   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 14   (req: >= 5)
Gene RIFs: 5   (req: > 3)
Antibodies: 78   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0