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Tbio
RCAN3
Calcipressin-3

Protein Summary
Description
Inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A. Could play a role during central nervous system development (By similarity).
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000374393
  • ENSP00000363514
  • ENSG00000117602
  • ENST00000374395
  • ENSP00000363516
  • ENST00000412742
  • ENSP00000391912
  • ENST00000425530
  • ENSP00000409540
  • ENST00000436717
  • ENSP00000414447
  • ENST00000538532
  • ENSP00000445401
  • ENST00000610732
  • ENSP00000479300
  • ENST00000616511
  • ENSP00000478174
  • ENST00000618490
  • ENSP00000484519
  • ENST00000630217
  • ENSP00000486836

Symbol
  • DSCR1L2
  • RCN3
  • MCIP3
  • hRCN3
  • DSCR1L2
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell type or tissue
0.86
transcription factor perturbation
0.84
small molecule perturbation
0.65
histone modification site profile
0.64
disease perturbation
0.62


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 10.55   (req: < 5)
Gene RIFs: 10   (req: <= 3)
Antibodies: 238   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 10.55   (req: >= 5)
Gene RIFs: 10   (req: > 3)
Antibodies: 238   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 7
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0