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Tbio
TMEM59L
Transmembrane protein 59-like

Protein Summary
Description
Modulates the O-glycosylation and complex N-glycosylation steps occurring during the Golgi maturation of APP. Inhibits APP transport to the cell surface and further shedding. This gene encodes a predicted type-I membrane glycoprotein. The encoded protein may play a role in functioning of the central nervous system. [provided by RefSeq, Jul 2008]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000262817
  • ENSP00000262817
  • ENSG00000105696
  • ENST00000600490
  • ENSP00000470879

Symbol
  • BSMAP
  • C19orf4
  • BSMAP
  • C19orf4
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor
0.74
virus perturbation
0.68
cell type or tissue
0.59
histone modification site profile
0.54
cell line
0.52


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 12.34   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 106   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 12.34   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 106   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Gene Ontology Terms (3)
Items per page:
10
1 – 3 of 3
GO Term
Evidence
Assigned by
Traceable Author Statement (TAS)
ProtInc
Traceable Author Statement (TAS)
ProtInc
Inferred from Electronic Annotation (IEA)
UniProtKB-SubCell
Protein-Protein Interactions (69)
1 – 10 of 69
MPPE1
Tbio
Family: Enzyme
Novelty: 0.25531915
p_int: 0.999421563
p_ni: 0.000577702
p_wrong: 7.35e-7
Data Source: BioPlex
MCOLN3
Tchem
Family: IC
Novelty: 0.05172316
p_int: 0.999398756
p_ni: 0.000576239
p_wrong: 0.000025005
Data Source: BioPlex
LRRC52
Tbio
Family: IC
Novelty: 0.4058938
p_int: 0.998538822
p_ni: 0.00142073
p_wrong: 0.000040448
Data Source: BioPlex
HTR3A
Tclin
Family: IC
Novelty: 0.00035394
p_int: 0.997778133
p_ni: 0.002221866
p_wrong: 1e-9
Score: 0.159
Data Source: BioPlex,STRINGDB
CD1E
Tbio
Novelty: 0.00231902
p_int: 0.996733735
p_ni: 0.003089988
p_wrong: 0.000176276
Data Source: BioPlex
ATP1B4
Tdark
Family: Transporter
Novelty: 0.01060988
p_int: 0.996610207
p_ni: 0.003260645
p_wrong: 0.000129148
Score: 0.183
Data Source: BioPlex,STRINGDB
HFE
Tbio
Novelty: 0.00040976
p_int: 0.994694544
p_ni: 0.005302302
p_wrong: 0.000003153
Data Source: BioPlex
CD1A
Tbio
Novelty: 0.00133941
p_int: 0.991645211
p_ni: 0.007349734
p_wrong: 0.001005055
Data Source: BioPlex
PCDHGB4
Tdark
Novelty: 0.62001206
p_int: 0.983951706
p_ni: 0.014791414
p_wrong: 0.00125688
Data Source: BioPlex
MUC1
Tbio
Novelty: 0.00029046
p_int: 0.980141019
p_ni: 0.017778292
p_wrong: 0.002080688
Score: 0.167
Data Source: BioPlex,STRINGDB
Publication Statistics
PubMed Score  12.34

PubMed score by year
PubTator Score  8.2

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer
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