KCND3
Potassium voltage-gated channel subfamily D member 3
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
protein domain | 1 | ||
molecular function | 0.94 | ||
disease perturbation | 0.68 | ||
PubMedID | 0.64 | ||
transcription factor | 0.61 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Cardiac conduction | ||||
Reactome | Muscle contraction | ||||
Reactome | Neuronal System | ||||
Reactome | Phase 1 - inactivation of fast Na+ channels | ||||
Reactome | Potassium Channels | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Cardiac conduction | ||||
Muscle contraction | ||||
Neuronal System | ||||
Phase 1 - inactivation of fast Na+ channels | ||||
Potassium Channels | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Physical Interaction (IPI) | BHF-UCL | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
electrocardiography | 1 | 3 | 167 | 96.7 | |||||
body mass index | 4 | 3 | 4 | 84.6 | |||||
P wave terminal force measurement | 1 | 2 | 0 | 118 | 84.5 | ||||
3 | 3 | 0 | 1.1 | 79.8 | |||||
waist-hip ratio | 2 | 2 | 2 | 70.4 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
electrocardiography | 167 | 96.7 | |||||
body mass index | 4 | 84.6 | |||||
P wave terminal force measurement | 0 | 118 | 84.5 | ||||
0 | 1.1 | 79.8 | |||||
waist-hip ratio | 2 | 70.4 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | potassium voltage-gated channel subfamily D member 3 | VGNC:8056 | 744303 | |||||
Mouse | MGI:1928743 | 56543 | ||||||
Rat | RGD:68394 | 65195 | ||||||
Dog | potassium voltage-gated channel subfamily D member 3 | VGNC:42240 | 403758 | |||||
Horse | potassium voltage-gated channel subfamily D member 3 | VGNC:19270 | 100058973 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | potassium voltage-gated channel subfamily D member 3 | |||||
Mouse | ||||||
Rat | ||||||
Dog | potassium voltage-gated channel subfamily D member 3 | |||||
Horse | potassium voltage-gated channel subfamily D member 3 | |||||
PMID | Year | Title |
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