ANAPC2
Anaphase-promoting complex subunit 2
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
biological process | 0.99 | ||
interacting protein | 0.91 | ||
disease perturbation | 0.79 | ||
histone modification site profile | 0.79 | ||
transcription factor binding site profile | 0.73 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
Click on a row in the table to change the structure displayed.
Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | APC-Cdc20 mediated degradation of Nek2A | ||||
Reactome | APC/C-mediated degradation of cell cycle proteins | ||||
Reactome | APC/C:Cdc20 mediated degradation of Cyclin B | ||||
Reactome | APC/C:Cdc20 mediated degradation of Securin | ||||
Reactome | APC/C:Cdc20 mediated degradation of mitotic proteins | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
APC-Cdc20 mediated degradation of Nek2A | ||||
APC/C-mediated degradation of cell cycle proteins | ||||
APC/C:Cdc20 mediated degradation of Cyclin B | ||||
APC/C:Cdc20 mediated degradation of Securin | ||||
APC/C:Cdc20 mediated degradation of mitotic proteins | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Electronic Annotation (IEA) | InterPro | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
glomerular filtration rate | 3 | 3 | 4 | 89.1 | |||||
creatinine measurement | 1 | 2 | 2 | 86.1 | |||||
reticulocyte measurement | 3 | 1 | 3 | 82.3 | |||||
reticulocyte count | 6 | 1 | 6 | 80.4 | |||||
serum urea measurement | 1 | 1 | 1 | 54.4 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
glomerular filtration rate | 4 | 89.1 | |||||
creatinine measurement | 2 | 86.1 | |||||
reticulocyte measurement | 3 | 82.3 | |||||
reticulocyte count | 6 | 80.4 | |||||
serum urea measurement | 1 | 54.4 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | anaphase promoting complex subunit 2 | VGNC:4610 | 465174 | |||||
Macaque | anaphase promoting complex subunit 2 | 706384 | ||||||
Mouse | MGI:2139135 | 99152 | ||||||
Rat | RGD:1305546 | 296558 | ||||||
Dog | anaphase promoting complex subunit 2 | VGNC:37849 | 491236 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | anaphase promoting complex subunit 2 | |||||
Macaque | anaphase promoting complex subunit 2 | |||||
Mouse | ||||||
Rat | ||||||
Dog | anaphase promoting complex subunit 2 | |||||
PMID | Year | Title |
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