Tbio RIMS3 Regulating synaptic membrane exocytosis protein 3

Protein Summary

Description

Regulates synaptic membrane exocytosis.

Uniprot Accession IDs

• Q9UJD0
• D3DPV8
• Q92511
• X5D7U7
• Nim3

Gene Name

• RIMS3

Ensembl ID

• ENST00000372683
• ENSP00000361768
• ENSG00000117016
• ENST00000372684
• ENSP00000361769

Symbol

• KIAA0237
• NIM3
• RIM3
• RIM 3

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
kinase perturbation	0.76
microRNA	0.65
cell type or tissue	0.6
small molecule perturbation	0.6
cell line	0.55

Protein Classes

PANTHER Classes

Protein / Enzyme Modulator / G-protein Modulator / Regulating Synaptic Membrane Exocytosis Protein 3

DTO Classes

Protein / Enzyme Modulator / G-protein Modulator / Regulating Synaptic Membrane Exocytosis Protein 3

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 21.25   (req: < 5)

Gene RIFs: 3   (req: <= 3)

Antibodies: 89   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 21.25   (req: >= 5)

Gene RIFs: 3   (req: > 3)

Antibodies: 89   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 8

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0