TRMT6
tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
kinase perturbation | 0.96 | ||
histone modification site profile | 0.9 | ||
interacting protein | 0.9 | ||
virus perturbation | 0.83 | ||
tissue sample | 0.67 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Metabolism of RNA | ||||
Reactome | tRNA modification in the nucleus and cytosol | ||||
Reactome | tRNA processing | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Metabolism of RNA | ||||
tRNA modification in the nucleus and cytosol | ||||
tRNA processing | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from High Throughput Direct Assay (HDA) | UniProtKB | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
age at menopause | 4 | 3 | 5 | 97.2 | |||||
1 | 1 | 0 | 1.2 | 42.3 | |||||
anti-Mullerian hormone measurement | 1 | 1 | 1 | 39.6 | |||||
Menorrhagia | 1 | 1 | 0 | 1.2 | 17.8 | ||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
age at menopause | 5 | 97.2 | |||||
0 | 1.2 | 42.3 | |||||
anti-Mullerian hormone measurement | 1 | 39.6 | |||||
Menorrhagia | 0 | 1.2 | 17.8 | ||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | tRNA methyltransferase 6 | VGNC:6289 | 747713 | |||||
Macaque | tRNA methyltransferase 6 | 718229 | ||||||
Mouse | MGI:1914176 | 66926 | ||||||
Rat | RGD:1308877 | 311441 | ||||||
Dog | tRNA methyltransferase 6 | VGNC:54738 | 485777 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | tRNA methyltransferase 6 | |||||
Macaque | tRNA methyltransferase 6 | |||||
Mouse | ||||||
Rat | ||||||
Dog | tRNA methyltransferase 6 | |||||
PMID | Year | Title |
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