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Tbio
PHF11
PHD finger protein 11

Protein Summary
Description
Positive regulator of Th1-type cytokine gene expression. This gene encodes a protein containing a PHD (plant homeodomain) type zinc finger. This gene has been identified in some studies as a candidate gene for asthma. Naturally-occurring readthrough transcription may occur from the upstream SETDB2 (SET domain bifurcated 2) gene to this locus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000357596
  • ENSP00000350209
  • ENSG00000136147
  • ENST00000378319
  • ENSP00000367570
  • ENST00000488958
  • ENSP00000417539

Symbol
  • BCAP
  • APY
  • BCAP
  • IGEL
  • IGER
  • IGHER
  • NYREN34
  • NY-REN-34
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
virus perturbation
1
transcription factor
0.73
histone modification site profile
0.68
transcription factor perturbation
0.61
cell line
0.6


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 19.42   (req: < 5)
Gene RIFs: 13   (req: <= 3)
Antibodies: 179   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 19.42   (req: >= 5)
Gene RIFs: 13   (req: > 3)
Antibodies: 179   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0