DAPK2
Death-associated protein kinase 2
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
molecular function | 0.95 | ||
co-expressed gene | 0.91 | ||
disease perturbation | 0.9 | ||
protein domain | 0.85 | ||
histone modification site profile | 0.84 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Apoptosis | ||||
Reactome | Caspase activation via Dependence Receptors in the absence of ligand | ||||
Reactome | Caspase activation via extrinsic apoptotic signalling pathway | ||||
Reactome | Programmed Cell Death | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Apoptosis | ||||
Caspase activation via Dependence Receptors in the absence of ligand | ||||
Caspase activation via extrinsic apoptotic signalling pathway | ||||
Programmed Cell Death | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Physical Interaction (IPI) | IntAct | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
apolipoprotein B measurement | 1 | 1 | 1 | 35 | |||||
high density lipoprotein cholesterol measurement | 1 | 1 | 1 | 17.6 | |||||
red blood cell distribution width | 2 | 1 | 2 | 17.5 | |||||
1 | 1 | 0 | 1 | 14.2 | |||||
BMI-adjusted waist circumference | 1 | 1 | 1 | 5 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
apolipoprotein B measurement | 1 | 35 | |||||
high density lipoprotein cholesterol measurement | 1 | 17.6 | |||||
red blood cell distribution width | 2 | 17.5 | |||||
0 | 1 | 14.2 | |||||
BMI-adjusted waist circumference | 1 | 5 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | death associated protein kinase 2 | VGNC:11853 | 747631 | |||||
Macaque | death associated protein kinase 2 | 706421 | ||||||
Mouse | MGI:1341297 | 13143 | ||||||
Horse | death associated protein kinase 2 | VGNC:17007 | 100066921 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | death associated protein kinase 2 | |||||
Macaque | death associated protein kinase 2 | |||||
Mouse | ||||||
Horse | death associated protein kinase 2 | |||||
PMID | Year | Title |
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