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Tbio
SAP30BP
SAP30-binding protein

Protein Summary
Description
Induces cell death. May act as a transcriptional corepressor of a gene related to cell survival. May be involved in the regulation of beta-2-microglobulin genes.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000355423
  • ENSP00000347592
  • ENSG00000161526
  • ENST00000584667
  • ENSP00000462116

Symbol
  • HCNGP
  • HTRG
  • HTRP
  • HTRG
  • HTRP
  • HCNGP
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
virus perturbation
1
kinase perturbation
0.91
histone modification site profile
0.9
transcription factor binding site profile
0.72
cell line
0.63


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 45.37   (req: < 5)
Gene RIFs: 9   (req: <= 3)
Antibodies: 245   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 45.37   (req: >= 5)
Gene RIFs: 9   (req: > 3)
Antibodies: 245   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0