Tdark RSPH14 Radial spoke head 14 homolog

Protein Summary

Description

This gene encodes a protein with no known function but with slight similarity to a yeast vacuolar protein. The gene is located in a region deleted in pediatric rhabdoid tumors of the brain, kidney and soft tissues, but mutations in this gene have not been associated with the disease. [provided by RefSeq, Jul 2008]

Uniprot Accession IDs

• Q9UHP6

Gene Name

• RSPH14

Ensembl ID

• ENST00000216036
• ENSP00000216036
• ENSG00000100218

Symbol

• RTDR1
• RTDR1

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
tissue sample	0.72
cell type or tissue	0.67
cell line	0.64
tissue	0.63
histone modification site profile	0.59

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.25   (req: < 5)

Gene RIFs: 0   (req: <= 3)

Antibodies: 147   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.25   (req: >= 5)

Gene RIFs: 0   (req: > 3)

Antibodies: 147   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0