Tbio NDRG3 Protein NDRG3

Protein Summary

Uniprot Accession IDs

• Q9UGV2
• A2A2S8
• E1P5U7
• E1P5U8
• Q5TH32
• Q96PL8
• Q96SM2
• Q9BXY7
• Q9H3N7
• Q9H411
• Q9H8J6

Gene Name

• NDRG3

Ensembl ID

• ENST00000349004
• ENSP00000345292
• ENSG00000101079
• ENST00000359675
• ENSP00000352703

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
kinase perturbation	0.97
transcription factor perturbation	0.94
tissue	0.71
histone modification site profile	0.69
disease perturbation	0.68

Protein Classes

PANTHER Classes

Protein / ... / Serine Protease / Protein Ndrg3

DTO Classes

Protein / Enzyme / Protease / Serine Protease / Protein Ndrg3

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 24.65   (req: < 5)

Gene RIFs: 20   (req: <= 3)

Antibodies: 125   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 24.65   (req: >= 5)

Gene RIFs: 20   (req: > 3)

Antibodies: 125   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0