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Tbio
CRCT1
Cysteine-rich C-terminal protein 1

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000368790
  • ENSP00000357779
  • ENSG00000169509

Symbol
  • C1orf42
  • NICE1
  • NICE1
  • NICE-1
  • C1orf42
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
PubMedID
0.62
cell type or tissue
0.6
gene perturbation
0.59
tissue
0.58
hub protein
0.44


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 10.48   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 81   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 10.48   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 81   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Protein-Protein Interactions (43)
1 – 10 of 43
SPRR1B
Tbio
Novelty:  0.0320028
Score:  0.723
Data Source:  STRINGDB
SPRR3
Tbio
Novelty:  0.0241484
Score:  0.702
Data Source:  STRINGDB
C1orf43
Tbio
Novelty:  0.13587458
Score:  0.7
Data Source:  STRINGDB
S100A7A
Tbio
Novelty:  0.06518939
Score:  0.694
Data Source:  STRINGDB
LCE2B
Tdark
Novelty:  0.88335558
Score:  0.682
Data Source:  STRINGDB
LCE3E
Tdark
Novelty:  0.72118892
Score:  0.677
Data Source:  STRINGDB
UBAP2L
Tbio
Novelty:  0.0568419
Score:  0.668
Data Source:  STRINGDB
SPRR1A
Tbio
Novelty:  0.04328986
Score:  0.661
Data Source:  STRINGDB
CRNN
Tbio
Novelty:  0.01648731
Score:  0.66
Data Source:  STRINGDB
SPRR2E
Tdark
Novelty:  0.78347788
Score:  0.653
Data Source:  STRINGDB
GWAS Traits (7)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
vitamin D measurement
3
6
6
97.4
4
4
0
1.6
92.3
3
3
0
1.3
91
1
3
0
1.5
90.2
childhood onset asthma
1
1
0
1.6
7.8
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
vitamin D measurement
6
97.4
0
1.6
92.3
0
1.3
91
0
1.5
90.2
childhood onset asthma
0
1.6
7.8
Publication Statistics
PubMed Score 10.48
PubMed score by year
PubTator Score 4.77
PubTator score by year