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Tbio
MIOX
Inositol oxygenase

IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 126.79   (req: < 5)
Gene RIFs: 9   (req: <= 3)
Antibodies: 251   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 126.79   (req: >= 5)
Gene RIFs: 9   (req: > 3)
Antibodies: 251   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 7
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (73)
IMPA1
Tclin
Family:  Enzyme
Novelty:  0.00766053
Score:  0.953
Data Source:  STRINGDB
AKR1A1
Tchem
Family:  Enzyme
Novelty:  0.0054436
Score:  0.949
Data Source:  STRINGDB
IMPA2
Tbio
Family:  Enzyme
Novelty:  0.03983031
Score:  0.943
Data Source:  STRINGDB
CDIPT
Tbio
Family:  Enzyme
Novelty:  0.00560887
Score:  0.929
Data Source:  STRINGDB
IMPAD1
Tbio
Family:  Enzyme
Novelty:  0.08211251
Score:  0.921
Data Source:  STRINGDB
GUSB
Tchem
Family:  Enzyme
Novelty:  0.00053974
Score:  0.847
Data Source:  STRINGDB
ISYNA1
Tbio
Family:  Enzyme
Novelty:  0.00302974
Score:  0.827
Data Source:  STRINGDB
KL
Tbio
Family:  Enzyme
Novelty:  0.00096954
Score:  0.822
Data Source:  STRINGDB
UGDH
Tbio
Family:  Enzyme
Novelty:  0.00284931
Score:  0.799
Data Source:  STRINGDB
ADM2
Tbio
Novelty:  0.00245573
Score:  0.781
Data Source:  STRINGDB
Pathways (8)
Inositol phosphate metabolism (R-HSA-1483249)

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Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Inositol phosphate metabolism
Reactome
Metabolism
Reactome
Synthesis of IP2, IP, and Ins in the cytosol
Name
Explore in Pharos
Explore in Source
Inositol phosphate metabolism
Metabolism
Synthesis of IP2, IP, and Ins in the cytosol
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (10)
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Items per page:
10
1 – 5 of 5
GO Term
Evidence
Assigned by
Inferred from Direct Assay (IDA)
UniProtKB
Inferred from Direct Assay (IDA)
UniProtKB
Inferred from Sequence or structural Similarity (ISS)
UniProtKB
Inferred from Sequence or structural Similarity (ISS)
UniProtKB
Inferred from Electronic Annotation (IEA)
Ensembl
Disease Associations ()
No disease associations found
GWAS Traits (24)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
mean corpuscular volume
5
7
8
99
mean reticulocyte volume
1
4
4
97.6
red blood cell distribution width
4
4
4
95.6
mean corpuscular hemoglobin
3
3
3
94.6
mean corpuscular hemoglobin concentration
2
2
2
91.5
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
mean corpuscular volume
8
99
mean reticulocyte volume
4
97.6
red blood cell distribution width
4
95.6
mean corpuscular hemoglobin
3
94.6
mean corpuscular hemoglobin concentration
2
91.5
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (11)
1 – 5 of 11
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Macaque
myo-inositol oxygenase
720668
Mouse
MGI:1891725
56727
Rat
RGD:628739
252899
Dog
myo-inositol oxygenase
VGNC:43240
481189
Horse
myo-inositol oxygenase
VGNC:20195
100056580
Species
Name
OMA
EggNOG
Inparanoid
Macaque
myo-inositol oxygenase
Mouse
Rat
Dog
myo-inositol oxygenase
Horse
myo-inositol oxygenase
Publication Statistics
PubMed Score 126.79
PubMed score by year
PubTator Score 22.94
PubTator score by year
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Related Publications
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0 of 0
PMID
Year
Title