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Tdark
NIPSNAP3A
Protein NipSnap homolog 3A

Protein Summary
Description
NIPSNAP3A belongs to a family of proteins with putative roles in vesicular transport (Buechler et al., 2004 [PubMed 15177564]).[supplied by OMIM, Mar 2008]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000374767
  • ENSP00000363899
  • ENSG00000136783

Symbol
  • NIPSNAP4
  • TASSC
  • HSPC299
  • NIPSNAP4
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
virus perturbation
0.85
histone modification site profile
0.72
kinase perturbation
0.71
tissue sample
0.71
tissue
0.55


Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.61   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 114   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.61   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 114   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (13)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
high density lipoprotein cholesterol measurement
10
26
30
1.4
99.5
apolipoprotein A 1 measurement
2
15
15
99.2
total cholesterol measurement
4
12
13
96.4
sleep duration
2
3
4
93.3
low density lipoprotein cholesterol measurement
3
4
4
79.9
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
high density lipoprotein cholesterol measurement
30
1.4
99.5
apolipoprotein A 1 measurement
15
99.2
total cholesterol measurement
13
96.4
sleep duration
4
93.3
low density lipoprotein cholesterol measurement
4
79.9
Orthologs (2)
1 – 2 of 2
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
nipsnap homolog 3A
VGNC:10125
737685
Cow
nipsnap homolog 3A
534363
Species
Name
OMA
EggNOG
Inparanoid
Chimp
nipsnap homolog 3A
Cow
nipsnap homolog 3A
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q9UFN0-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Gene Ontology Terms (3)
Items per page:
10
1 – 3 of 3
GO Term
Evidence
Assigned by
Inferred from High Throughput Direct Assay (HDA)
UniProtKB
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Electronic Annotation (IEA)
UniProtKB-SubCell
Protein-Protein Interactions (33)
1 – 10 of 33
KCMF1
Tbio
Family:  Enzyme
Novelty:  0.05485534
p_int:  0.999952294
p_ni:  0.000047706
Score:  0.186
Data Source:  BioPlex,STRINGDB
FGL1
Tbio
Novelty:  0.02650803
p_int:  0.998138503
p_ni:  0.001861497
Data Source:  BioPlex
C2orf54
Tdark
Novelty:  1.82354708
p_int:  0.994371488
p_ni:  0.005628426
p_wrong:  8.6e-8
Score:  0.39
Data Source:  BioPlex,STRINGDB
MRPL12
Tbio
Novelty:  0.10646542
p_int:  0.989856501
p_ni:  0.010143499
Data Source:  BioPlex
HSPD1
Tbio
Novelty:  0.00018924
p_int:  0.988541295
p_ni:  0.011458705
Data Source:  BioPlex
NIT1
Tbio
Family:  Enzyme
Novelty:  0.00498587
p_int:  0.985205462
p_ni:  0.014794538
Data Source:  BioPlex
ACAD9
Tbio
Family:  Enzyme
Novelty:  0.03238308
p_int:  0.968394953
p_ni:  0.031604949
p_wrong:  9.9e-8
Data Source:  BioPlex
ATP5F1D
Tbio
Family:  Enzyme
Novelty:  0.07296539
p_int:  0.964268973
p_ni:  0.035731022
p_wrong:  5e-9
Score:  0.199
Data Source:  BioPlex,STRINGDB
OTC
Tchem
Family:  Enzyme
Novelty:  0.00544004
p_int:  0.957064983
p_ni:  0.042935017
Score:  0.173
Data Source:  BioPlex,STRINGDB
PPA2
Tbio
Family:  Enzyme
Novelty:  0.01790138
p_int:  0.892350267
p_ni:  0.107649733
Score:  0.192
Data Source:  BioPlex,STRINGDB
Publication Statistics
PubMed Score  1.61

PubMed score by year
PubTator Score  0.54

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer
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