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Tchem
STK17A
Serine/threonine-protein kinase 17A

Protein Summary
Description
Acts as a positive regulator of apoptosis. Also acts as a regulator of cellular reactive oxygen species. This gene is a member of the DAP kinase-related apoptosis-inducing protein kinase family and encodes an autophosphorylated nuclear protein with a protein kinase domain. The protein has apoptosis-inducing activity. [provided by RefSeq, Jul 2008]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000319357
  • ENSP00000319192
  • ENSG00000164543
  • ENST00000648544
  • ENSP00000497301

Symbol
  • DRAK1
  • DRAK1
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
small molecule
0.92
molecular function
0.9
co-expressed gene
0.89
PubMedID
0.87
protein domain
0.73


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 26.17   (req: < 5)
Gene RIFs: 14   (req: <= 3)
Antibodies: 310   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 26.17   (req: >= 5)
Gene RIFs: 14   (req: > 3)
Antibodies: 310   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 8
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligands: 46
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drugs: 2