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Tdark
ZMAT5
Zinc finger matrin-type protein 5

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000344318
  • ENSP00000344241
  • ENSG00000100319

Symbol
  • ZC3H19
  • SNRNP20
  • U11/U12-20K
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.91
transcription factor binding site profile
0.76
small molecule perturbation
0.69
transcription factor
0.67
tissue sample
0.61


Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.65   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 54   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.65   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 54   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (13)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
self reported educational attainment
2
2
2
78.2
serum non-albumin protein measurement
1
2
2
71.7
reticulocyte count
1
1
1
70.2
glomerular filtration rate
1
1
1
63.4
2
1
0
1.1
60.5
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
self reported educational attainment
2
78.2
serum non-albumin protein measurement
2
71.7
reticulocyte count
1
70.2
glomerular filtration rate
1
63.4
0
1.1
60.5
Orthologs (13)
1 – 5 of 13
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
zinc finger matrin-type 5
VGNC:7808
458746
Mouse
MGI:1914428
67178
Rat
RGD:1559774
501926
Dog
zinc finger matrin-type 5
VGNC:48642
477536
Horse
zinc finger matrin-type 5
VGNC:25245
100058933
Species
Name
OMA
EggNOG
Inparanoid
Chimp
zinc finger matrin-type 5
Mouse
Rat
Dog
zinc finger matrin-type 5
Horse
zinc finger matrin-type 5
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q9UDW3-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Pathways (4)
Metabolism of RNA (R-HSA-8953854)

Click on a row in the table to change the structure displayed.

Items per page:
1 – 4 of 4
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Metabolism of RNA
Reactome
Processing of Capped Intron-Containing Pre-mRNA
Reactome
mRNA Splicing
Reactome
mRNA Splicing - Minor Pathway
Name
Explore in Pharos
Explore in Source
Metabolism of RNA
Processing of Capped Intron-Containing Pre-mRNA
mRNA Splicing
mRNA Splicing - Minor Pathway
Gene Ontology Terms (5)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
InterPro
Protein-Protein Interactions (116)
1 – 10 of 116
PHF5A
Tbio
Family:  Epigenetic
Novelty:  0.02989472
p_int:  0.999999929
p_ni:  5.6e-8
p_wrong:  1.5e-8
Score:  0.775
Data Source:  BioPlex,STRINGDB
SNRPN
Tbio
Novelty:  0.002157
p_int:  0.999999663
p_ni:  3.22e-7
p_wrong:  1.5e-8
Score:  0.915
Data Source:  BioPlex,STRINGDB
DENND4B
Tbio
Novelty:  1.70486718
p_int:  0.999991023
p_ni:  4.46e-7
p_wrong:  0.00000853
Score:  0.252
Data Source:  BioPlex,STRINGDB
SNRPF
Tdark
Novelty:  0.17624854
p_int:  0.999984245
p_ni:  0.000015755
Score:  0.992
Data Source:  BioPlex,STRINGDB
ZCRB1
Tdark
Novelty:  0.37592387
p_int:  0.999970715
p_ni:  0.000028919
p_wrong:  3.66e-7
Score:  0.946
Data Source:  BioPlex,STRINGDB
PDCD7
Tbio
Novelty:  0.15531712
p_int:  0.999936133
p_ni:  0.000047735
p_wrong:  0.000016132
Score:  0.985
Data Source:  BioPlex,STRINGDB
ZRSR2
Tbio
Novelty:  0.03449891
p_int:  0.999935567
p_ni:  0.000001907
p_wrong:  0.000062526
Score:  0.972
Data Source:  BioPlex,STRINGDB
RNPC3
Tbio
Novelty:  0.07154673
p_int:  0.999924881
p_ni:  0.000075044
p_wrong:  7.6e-8
Score:  0.992
Data Source:  BioPlex,STRINGDB
SNRPGP15
Tdark
p_int:  0.999915917
p_ni:  0.000084083
Data Source:  BioPlex
SNRNP48
Tbio
Novelty:  0.16395917
p_int:  0.999819003
p_ni:  0.000180995
p_wrong:  2e-9
Score:  0.992
Data Source:  BioPlex,STRINGDB
Publication Statistics
PubMed Score  0.65

PubMed score by year
PubTator Score  0.33

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer
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