UQCR10
Cytochrome b-c1 complex subunit 9
Protein Summary
This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This subunit interacts with cytochrome c1 (By similarity). UCRC is a subunit of mitochondrial complex III (ubiquinol-cytochrome c reductase; EC 1.10.2.2), which forms the middle segment of the respiratory chain of the inner mitochondrial membrane (Schagger et al., 1995 [PubMed 8592474]).[supplied by OMIM, Mar 2008]
- ENST00000330029
- ENSP00000332887
- ENSG00000184076
- ENST00000401406
- ENSP00000384962
- UCRC
- QCR9
- UCRC
- HSPC051
- HSPC119
- HSPC151
- UCCR7.2
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
transcription factor perturbation | 0.99 | ||
kinase perturbation | 0.95 | ||
histone modification site profile | 0.94 | ||
ligand (protein) perturbation | 0.83 | ||
virus perturbation | 0.79 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 23.04 (req: < 5)
Gene RIFs: 4 (req: <= 3)
Antibodies: 71 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 23.04 (req: >= 5)
Gene RIFs: 4 (req: > 3)
Antibodies: 71 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 4
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
Related Tools
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
Active Ligands (0)
Protein-Protein Interactions (175)
PTGES2
Family: Enzyme
Novelty: 0.01415352
p_int: 0.817757177
p_ni: 0.182242317
p_wrong: 5.06e-7
Data Source: BioPlex
Nearest Tclin Targets
Pathways (14)
Reactome (4)
KEGG (8)
WikiPathways (2)
Click on a row in the table to change the structure displayed.
Data Source | Name | Explore in Pharos | Explore in Source | ||
|---|---|---|---|---|---|
Reactome | Metabolism | ||||
Reactome | Respiratory electron transport | ||||
Reactome | Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. | ||||
Reactome | The citric acid (TCA) cycle and respiratory electron transport | ||||
Name | Explore in Pharos | Explore in Source | ||
|---|---|---|---|---|
Metabolism | ||||
Respiratory electron transport | ||||
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. | ||||
The citric acid (TCA) cycle and respiratory electron transport | ||||
Viral Interactions (0)
Gene Ontology Terms (6)
Functions (1)
Components (2)
Processes (3)
GO Term | Evidence | Assigned by | ||
|---|---|---|---|---|
Non-traceable Author Statement (NAS) | UniProtKB | |||
Disease Associations ()
GWAS Traits (13)
Items per page:
1 – 5 of 13
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
|---|---|---|---|---|---|---|---|---|---|
reticulocyte measurement | 2 | 2 | 2 | 79.6 | |||||
self reported educational attainment | 2 | 2 | 2 | 78.2 | |||||
serum non-albumin protein measurement | 1 | 2 | 2 | 71.7 | |||||
reticulocyte count | 2 | 2 | 2 | 71.5 | |||||
glomerular filtration rate | 1 | 1 | 1 | 63.4 | |||||
Items per page:
1 – 5 of 13
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
|---|---|---|---|---|---|---|---|
reticulocyte measurement | 2 | 79.6 | |||||
self reported educational attainment | 2 | 78.2 | |||||
serum non-albumin protein measurement | 2 | 71.7 | |||||
reticulocyte count | 2 | 71.5 | |||||
glomerular filtration rate | 1 | 63.4 | |||||
Find similar targets by:
IDG Resources
Orthologs (9)
1 – 5 of 9
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
|---|---|---|---|---|---|---|---|---|
Mouse | MGI:1913402 | 66152 | ||||||
Rat | RGD:1595126 | 685322 | ||||||
Dog | ubiquinol-cytochrome c reductase, complex III subunit X | VGNC:48162 | 486347 | |||||
Cow | ubiquinol-cytochrome c reductase, complex III subunit X | VGNC:36693 | 616109 | |||||
Pig | ubiquinol-cytochrome c reductase complex 7.2 kDa protein | 100155687 | ||||||
Species | Name | OMA | EggNOG | Inparanoid | ||
|---|---|---|---|---|---|---|
Mouse | ||||||
Rat | ||||||
Dog | ubiquinol-cytochrome c reductase, complex III subunit X | |||||
Cow | ubiquinol-cytochrome c reductase, complex III subunit X | |||||
Pig | ubiquinol-cytochrome c reductase complex 7.2 kDa protein | |||||
Publication Statistics
PubMed Score 23.04
PubMed score by year
PubTator Score 4.06
PubTator score by year
Related Publications
Text Mined References (14)
GeneRif Annotations (4)
Items per page:
0 of 0
PMID | Year | Title |
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