UQCR10
Cytochrome b-c1 complex subunit 9
Protein Summary
This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This subunit interacts with cytochrome c1 (By similarity). UCRC is a subunit of mitochondrial complex III (ubiquinol-cytochrome c reductase; EC 1.10.2.2), which forms the middle segment of the respiratory chain of the inner mitochondrial membrane (Schagger et al., 1995 [PubMed 8592474]).[supplied by OMIM, Mar 2008]
- ENST00000330029
- ENSP00000332887
- ENSG00000184076
- ENST00000401406
- ENSP00000384962
- UCRC
- QCR9
- UCRC
- HSPC051
- HSPC119
- HSPC151
- UCCR7.2
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
transcription factor perturbation | 0.99 | ||
kinase perturbation | 0.95 | ||
histone modification site profile | 0.94 | ||
ligand (protein) perturbation | 0.83 | ||
virus perturbation | 0.79 | ||
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 23.04 (req: < 5)
Gene RIFs: 4 (req: <= 3)
Antibodies: 71 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 23.04 (req: >= 5)
Gene RIFs: 4 (req: > 3)
Antibodies: 71 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 4
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools
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Protein-Protein Interactions (175)
1 – 10 of 175
PTGES2
Family: Enzyme
Novelty: 0.01415352
p_int: 0.817757177
p_ni: 0.182242317
p_wrong: 5.06e-7
Data Source: BioPlex
CYC1
Novelty: 0.01369865
Score: 0.999
Data Source: STRINGDB
UQCRC2
Family: Enzyme
Novelty: 0.01584406
Score: 0.999
Data Source: STRINGDB
UQCRQ
Novelty: 0.04392627
Score: 0.999
Data Source: STRINGDB
UQCRB
Novelty: 0.02933046
Score: 0.999
Data Source: STRINGDB
UQCR11
Novelty: 0.08583842
Score: 0.999
Data Source: STRINGDB
UQCRFS1
Novelty: 0.00341256
Score: 0.999
Data Source: STRINGDB
UQCRH
Novelty: 0.04494433
Score: 0.999
Data Source: STRINGDB
UQCRC1
Family: Enzyme
Novelty: 0.01746759
Score: 0.999
Data Source: STRINGDB
MT-CYB
Novelty: 0.00012093
Score: 0.998
Data Source: STRINGDB
Pathways (14)
Reactome (4)
KEGG (8)
WikiPathways (2)
Click on a row in the table to change the structure displayed.
Items per page:
1 – 4 of 4
Data Source | Name | Explore in Pharos | Explore in Source | ||
|---|---|---|---|---|---|
Reactome | Metabolism | ||||
Reactome | Respiratory electron transport | ||||
Reactome | Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. | ||||
Reactome | The citric acid (TCA) cycle and respiratory electron transport | ||||
Name | Explore in Pharos | Explore in Source | ||
|---|---|---|---|---|
Metabolism | ||||
Respiratory electron transport | ||||
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. | ||||
The citric acid (TCA) cycle and respiratory electron transport | ||||
Gene Ontology Terms (6)
Functions (1)
Components (2)
Processes (3)
Items per page:
10
1 – 1 of 1
GO Term | Evidence | Assigned by | ||
|---|---|---|---|---|
Non-traceable Author Statement (NAS) | UniProtKB | |||
GWAS Traits (13)
Items per page:
1 – 5 of 13
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
|---|---|---|---|---|---|---|---|---|---|
reticulocyte measurement | 2 | 2 | 2 | 79.6 | |||||
self reported educational attainment | 2 | 2 | 2 | 78.2 | |||||
serum non-albumin protein measurement | 1 | 2 | 2 | 71.7 | |||||
reticulocyte count | 2 | 2 | 2 | 71.5 | |||||
glomerular filtration rate | 1 | 1 | 1 | 63.4 | |||||
Items per page:
1 – 5 of 13
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
|---|---|---|---|---|---|---|---|
reticulocyte measurement | 2 | 79.6 | |||||
self reported educational attainment | 2 | 78.2 | |||||
serum non-albumin protein measurement | 2 | 71.7 | |||||
reticulocyte count | 2 | 71.5 | |||||
glomerular filtration rate | 1 | 63.4 | |||||
Find similar targets by:
UniProt Keyword
No Header | No Header | ||
|---|---|---|---|
Orthologs (9)
1 – 5 of 9
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
|---|---|---|---|---|---|---|---|---|
Mouse | MGI:1913402 | 66152 | ||||||
Rat | RGD:1595126 | 685322 | ||||||
Dog | ubiquinol-cytochrome c reductase, complex III subunit X | VGNC:48162 | 486347 | |||||
Cow | ubiquinol-cytochrome c reductase, complex III subunit X | VGNC:36693 | 616109 | |||||
Pig | ubiquinol-cytochrome c reductase complex 7.2 kDa protein | 100155687 | ||||||
Species | Name | OMA | EggNOG | Inparanoid | ||
|---|---|---|---|---|---|---|
Mouse | ||||||
Rat | ||||||
Dog | ubiquinol-cytochrome c reductase, complex III subunit X | |||||
Cow | ubiquinol-cytochrome c reductase, complex III subunit X | |||||
Pig | ubiquinol-cytochrome c reductase complex 7.2 kDa protein | |||||
Publication Statistics
PubMed Score 23.04
PubMed score by year
PubTator Score 4.06
PubTator score by year