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Tdark
NKX1-2
NK1 transcription factor-related protein 2

Protein Summary
Description
May function in cell specification, particularly in the CNS.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000451024
  • ENSP00000451945
  • ENSG00000229544

Symbol
  • C10orf121
  • NKX1.1
  • NKX-1.1
  • C10orf121
  • bB238F13.2
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell type or tissue
0.72
protein domain
0.58
PubMedID
0.54
tissue
0.48
transcription factor binding site profile
0.4


Related Tools
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.42   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 80   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.42   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 80   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Orthologs (5)
1 – 5 of 5
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Mouse
MGI:104806
20231
Rat
RGD:1306744
293568
Dog
NK1 homeobox 2
VGNC:43832
486929
Cow
NK1 homeobox 2
VGNC:32098
617982
Anole lizard
NK1 homeobox 2 [Source:HGNC Symbol;Acc:HGNC:31652]
Species
Name
OMA
EggNOG
Inparanoid
Mouse
Rat
Dog
NK1 homeobox 2
Cow
NK1 homeobox 2
Anole lizard
NK1 homeobox 2 [Source:HGNC Symbol;Acc:HGNC:31652]
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q9UD57-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Protein-Protein Interactions (9)
1 – 9 of 9
APCDD1
Tbio
Novelty:  0.25122542
Score:  0.508
Data Source:  STRINGDB
ZNF232
Tdark
Family:  TF
Novelty:  0.68288358
Score:  0.465
Data Source:  STRINGDB
RIPK4
Tchem
Family:  Kinase
Novelty:  0.00818379
Score:  0.443
Data Source:  STRINGDB
RIPK1
Tchem
Family:  Kinase
Novelty:  0.00230565
Score:  0.443
Data Source:  STRINGDB
RHOXF2B
Tdark
Family:  TF
Novelty:  1.08207436
Score:  0.423
Data Source:  STRINGDB
FOXB1
Tbio
Family:  TF
Novelty:  0.04489092
Score:  0.419
Data Source:  STRINGDB
SEBOX
Tbio
Family:  TF
Novelty:  0.12741718
Score:  0.41
Data Source:  STRINGDB
GRHL3
Tbio
Family:  TF
Novelty:  0.01447204
Score:  0.406
Data Source:  STRINGDB
HIPK4
Tchem
Family:  Kinase
Novelty:  0.28272299
Score:  0.405
Data Source:  STRINGDB
Publication Statistics
PubMed Score  3.42

PubMed score by year
PubTator Score  2.22

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer