UBA2
SUMO-activating enzyme subunit 2
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
drug perturbation | 0.99 | ||
co-expressed gene | 0.98 | ||
molecular function | 0.97 | ||
protein domain | 0.97 | ||
disease perturbation | 0.87 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Metabolism of proteins | ||||
Reactome | Post-translational protein modification | ||||
Reactome | Processing and activation of SUMO | ||||
Reactome | SUMO is conjugated to E1 (UBA2:SAE1) | ||||
Reactome | SUMO is transferred from E1 to E2 (UBE2I, UBC9) | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Metabolism of proteins | ||||
Post-translational protein modification | ||||
Processing and activation of SUMO | ||||
SUMO is conjugated to E1 (UBA2:SAE1) | ||||
SUMO is transferred from E1 to E2 (UBE2I, UBC9) | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Physical Interaction (IPI) | CAFA | |||
Inferred from Physical Interaction (IPI) | CAFA | |||
Inferred from Physical Interaction (IPI) | CAFA | |||
Inferred from Mutant Phenotype (IMP) | CAFA | |||
Inferred from Mutant Phenotype (IMP) | CAFA | |||
Inferred from Mutant Phenotype (IMP) | CAFA | |||
Traceable Author Statement (TAS) | ProtInc | |||
Inferred from Electronic Annotation (IEA) | InterPro | |||
Inferred from Electronic Annotation (IEA) | Ensembl | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
electrocardiography | 1 | 1 | 1 | 15.8 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
electrocardiography | 1 | 15.8 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | ubiquitin like modifier activating enzyme 2 | VGNC:7494 | 468823 | |||||
Macaque | ubiquitin like modifier activating enzyme 2 | 705808 | ||||||
Mouse | MGI:1858313 | 50995 | ||||||
Rat | RGD:1312023 | 308508 | ||||||
Dog | ubiquitin like modifier activating enzyme 2 | VGNC:48037 | 476490 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | ubiquitin like modifier activating enzyme 2 | |||||
Macaque | ubiquitin like modifier activating enzyme 2 | |||||
Mouse | ||||||
Rat | ||||||
Dog | ubiquitin like modifier activating enzyme 2 | |||||
PMID | Year | Title |
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