UPB1
Beta-ureidopropionase
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
gene perturbation | 0.81 | ||
kinase perturbation | 0.66 | ||
transcription factor | 0.63 | ||
cell line | 0.57 | ||
tissue sample | 0.53 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Metabolism | ||||
Reactome | Metabolism of nucleotides | ||||
Reactome | Nucleobase catabolism | ||||
Reactome | Pyrimidine catabolism | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Metabolism | ||||
Metabolism of nucleotides | ||||
Nucleobase catabolism | ||||
Pyrimidine catabolism | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Experiment (EXP) | Reactome | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
serum gamma-glutamyl transferase measurement | 8 | 19 | 20 | 9.5 | 99.9 | ||||
tea consumption measurement | 3 | 3 | 4 | 92.2 | |||||
coffee consumption measurement | 3 | 3 | 3 | 89.1 | |||||
liver fibrosis measurement | 1 | 1 | 1 | 82.3 | |||||
protein measurement | 1 | 1 | 1 | 72.1 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
serum gamma-glutamyl transferase measurement | 20 | 9.5 | 99.9 | ||||
tea consumption measurement | 4 | 92.2 | |||||
coffee consumption measurement | 3 | 89.1 | |||||
liver fibrosis measurement | 1 | 82.3 | |||||
protein measurement | 1 | 72.1 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | beta-ureidopropionase 1 | VGNC:10415 | 747532 | |||||
Macaque | beta-ureidopropionase 1 | 707752 | ||||||
Mouse | MGI:2143535 | 103149 | ||||||
Dog | beta-ureidopropionase 1 | VGNC:48149 | 486398 | |||||
Horse | beta-ureidopropionase 1 | VGNC:24803 | 100053177 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | beta-ureidopropionase 1 | |||||
Macaque | beta-ureidopropionase 1 | |||||
Mouse | ||||||
Dog | beta-ureidopropionase 1 | |||||
Horse | beta-ureidopropionase 1 | |||||
PMID | Year | Title |
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