NLK
Serine/threonine-protein kinase NLK
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
molecular function | 1 | ||
protein domain | 0.85 | ||
virus perturbation | 0.83 | ||
transcription factor | 0.79 | ||
disease perturbation | 0.74 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Beta-catenin independent WNT signaling | ||||
Reactome | Ca2+ pathway | ||||
Reactome | Signal Transduction | ||||
Reactome | Signaling by WNT | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Beta-catenin independent WNT signaling | ||||
Ca2+ pathway | ||||
Signal Transduction | ||||
Signaling by WNT | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Physical Interaction (IPI) | UniProtKB | |||
Inferred from Physical Interaction (IPI) | UniProtKB | |||
Inferred from Sequence or structural Similarity (ISS) | UniProtKB | |||
Inferred from Sequence or structural Similarity (ISS) | UniProtKB | |||
Inferred from Sequence or structural Similarity (ISS) | UniProtKB | |||
Inferred from Sequence or structural Similarity (ISS) | UniProtKB | |||
Traceable Author Statement (TAS) | ProtInc | |||
Traceable Author Statement (TAS) | Reactome | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
body mass index | 1 | 1 | 1 | 31.4 | |||||
sporadic amyotrophic lateral sclerosis | 1 | 1 | 0 | 1.2 | 26.1 | ||||
blood protein measurement | 1 | 1 | 1 | 9.8 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
body mass index | 1 | 31.4 | |||||
sporadic amyotrophic lateral sclerosis | 0 | 1.2 | 26.1 | ||||
blood protein measurement | 1 | 9.8 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | nemo like kinase | VGNC:9477 | 739132 | |||||
Macaque | nemo like kinase | 677693 | ||||||
Mouse | MGI:1201387 | 18099 | ||||||
Rat | RGD:1561602 | 497961 | ||||||
Dog | nemo like kinase | VGNC:43841 | 491160 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | nemo like kinase | |||||
Macaque | nemo like kinase | |||||
Mouse | ||||||
Rat | ||||||
Dog | nemo like kinase | |||||
PMID | Year | Title |
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