Tbio DEC1 Deleted in esophageal cancer 1

Protein Summary

Description

Candidate tumor suppressor. The function of this gene is not known. This gene is located in a region commonly deleted in esophageal squamous cell carcinomas. Gene expression is reduced or absent in these carcinomas and thus this is a candidate tumor suppressor gene for esophageal squamous cell carcinomas. [provided by RefSeq, Jul 2008]

Uniprot Accession IDs

• Q9P2X7

Gene Name

• DEC1

Ensembl ID

• ENST00000648722
• ENSP00000497207
• ENSG00000173077

Symbol

• CTS9
• CTS9

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
cellular component	0.64
cell line	0.51
biological term	0.45
disease	0.44
phenotype	0.42

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 13.24   (req: < 5)

Gene RIFs: 9   (req: <= 3)

Antibodies: 4   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 13.24   (req: >= 5)

Gene RIFs: 9   (req: > 3)

Antibodies: 4   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0