Tdark RCOR3 REST corepressor 3

Protein Summary

Description

May act as a component of a corepressor complex that represses transcription.

Uniprot Accession IDs

• Q9P2K3
• B3KYA2
• B4DYY7
• Q5VT47
• Q7L9I5
• Q8N5U3
• Q9NV83

Gene Name

• RCOR3

Ensembl ID

• ENST00000367005
• ENSP00000355972
• ENSG00000117625
• ENST00000367006
• ENSP00000355973
• ENST00000419091
• ENSP00000413929
• ENST00000452621
• ENSP00000398558

Symbol

• KIAA1343

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
transcription factor perturbation	0.96
histone modification site profile	0.91
ligand (protein) perturbation	0.83
transcription factor binding site profile	0.75
cell type or tissue	0.7

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.22   (req: < 5)

Gene RIFs: 2   (req: <= 3)

Antibodies: 93   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.22   (req: >= 5)

Gene RIFs: 2   (req: > 3)

Antibodies: 93   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0