ARHGAP20
Rho GTPase-activating protein 20
Protein Summary
GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. The protein encoded by this gene is an activator of RHO-type GTPases, transducing a signal from RAP1 to RHO and impacting neurite outgrowth. [provided by RefSeq, Sep 2016]
- ENST00000260283
- ENSP00000260283
- ENSG00000137727
- ENST00000524756
- ENSP00000432076
- ENST00000527598
- ENSP00000431399
- ENST00000528829
- ENSP00000436319
- ENST00000533353
- ENSP00000436522
- KIAA1391
- RARHOGAP
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
microRNA | 0.93 | ||
gene perturbation | 0.85 | ||
protein domain | 0.85 | ||
tissue sample | 0.64 | ||
PubMedID | 0.55 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 7.76 (req: < 5)
Gene RIFs: 4 (req: <= 3)
Antibodies: 114 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 7.76 (req: >= 5)
Gene RIFs: 4 (req: > 3)
Antibodies: 114 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 3
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0