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Tbio
CHPF2
Chondroitin sulfate glucuronyltransferase

Protein Summary
Description
Transfers glucuronic acid (GlcUA) from UDP-GlcUA to N-acetylgalactosamine residues on the non-reducing end of the elongating chondroitin polymer. Has no N-acetylgalactosaminyltransferase activity.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000035307
  • ENSP00000035307
  • ENSG00000033100

Symbol
  • CHSY3
  • CSGLCAT
  • KIAA1402
  • ChSy-3
  • chPF-2
  • CSGlcAT
  • CSGLCA-T
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
pathway
0.92
transcription factor perturbation
0.8
kinase perturbation
0.76
transcription factor binding site profile
0.69
cell type or tissue
0.66


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 7.55   (req: < 5)
Gene RIFs: 4   (req: <= 3)
Antibodies: 95   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 7.55   (req: >= 5)
Gene RIFs: 4   (req: > 3)
Antibodies: 95   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0