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Tdark
ZNFX1
NFX1-type zinc finger-containing protein 1

Protein Classes
Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000371752
  • ENSP00000360817
  • ENSG00000124201
  • ENST00000396105
  • ENSP00000379412

Symbol
  • KIAA1404
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
virus perturbation
1
transcription factor binding site profile
0.94
disease perturbation
0.79
cell line
0.68
transcription factor perturbation
0.68


Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 17.76   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 24   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 17.76   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 24   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (12)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
body height
3
3
3
90.8
intelligence
6
9
4
5.7
78.6
electrocardiography
1
1
33
75.7
depressive symptom measurement
2
1
2
48.5
wellbeing measurement
1
1
1
47.7
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
body height
3
90.8
intelligence
4
5.7
78.6
electrocardiography
33
75.7
depressive symptom measurement
2
48.5
wellbeing measurement
1
47.7
Orthologs (12)
1 – 5 of 12
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
zinc finger NFX1-type containing 1
VGNC:10066
458321
Macaque
zinc finger NFX1-type containing 1
703746
Mouse
MGI:2138982
98999
Rat
RGD:1306344
296384
Dog
zinc finger NFX1-type containing 1
VGNC:48834
477260
Species
Name
OMA
EggNOG
Inparanoid
Chimp
zinc finger NFX1-type containing 1
Macaque
zinc finger NFX1-type containing 1
Mouse
Rat
Dog
zinc finger NFX1-type containing 1
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q9P2E3-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Protein-Protein Interactions (61)
1 – 10 of 61
STRAP
Tbio
Family:  Enzyme
Novelty:  0.0336013
p_int:  0.999999976
p_ni:  1.4e-8
p_wrong:  1e-8
Score:  0.214
Data Source:  BioPlex,STRINGDB
OS9
Tbio
Novelty:  0.01490339
p_int:  0.999948886
p_ni:  0.000020852
p_wrong:  0.000030262
Data Source:  BioPlex
RBBP7
Tbio
Novelty:  0.01795364
Score:  0.91
Data Source:  STRINGDB
HDAC1
Tclin
Family:  Epigenetic
Novelty:  0.00065244
Score:  0.906
Data Source:  STRINGDB
HDAC2
Tclin
Family:  Epigenetic
Novelty:  0.0011024
Score:  0.906
Data Source:  STRINGDB
UBE3A
Tbio
Family:  Enzyme
Novelty:  0.00149368
Score:  0.904
Data Source:  STRINGDB
SIN3A
Tbio
Novelty:  0.00747207
Score:  0.903
Data Source:  STRINGDB
SIN3B
Tbio
Novelty:  0.04097105
Score:  0.903
Data Source:  STRINGDB
SAP18
Tbio
Family:  Enzyme
Novelty:  0.03918373
Score:  0.902
Data Source:  STRINGDB
RBBP4
Tbio
Novelty:  0.01062843
Score:  0.902
Data Source:  STRINGDB
Publication Statistics
PubMed Score  17.76

PubMed score by year
PubTator Score  4.07

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer
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