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Tdark
COL20A1
Collagen alpha-1(XX) chain

Protein Summary
Description
Probable collagen protein.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000358894
  • ENSP00000351767
  • ENSG00000101203
  • ENST00000422202
  • ENSP00000414753

Symbol
  • KIAA1510
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
protein domain
0.85
cellular component
0.74
cell type or tissue
0.56
transcription factor
0.51
virus perturbation
0.5


Protein Classes
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.62   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 179   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.62   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 179   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (94)
GLS
Tchem
Family:  Enzyme
Novelty:  0.00321692
p_int:  0.999995342
p_ni:  0.000004658
p_wrong:  1e-9
Data Source:  BioPlex
GGACT
Tbio
Family:  Enzyme
Novelty:  0.20580326
p_int:  0.999866464
p_ni:  0.00013353
p_wrong:  5e-9
Score:  0.517
Data Source:  BioPlex,STRINGDB
TSC2
Tbio
Novelty:  0.00067416
p_int:  0.9997743
p_ni:  0.000225691
p_wrong:  9e-9
Score:  0.188
Data Source:  BioPlex,STRINGDB
COL14A1
Tbio
Novelty:  0.01760399
p_int:  0.999659907
p_ni:  0.000340093
Score:  0.918
Data Source:  BioPlex,STRINGDB
ATP5MC3
Tdark
Family:  Enzyme
Novelty:  0.04850603
p_int:  0.997904114
p_ni:  0.002000653
p_wrong:  0.000095233
Score:  0.205
Data Source:  BioPlex,STRINGDB
NRP2
Tbio
Novelty:  0.00764179
p_int:  0.988263745
p_ni:  0.011736252
p_wrong:  3e-9
Data Source:  BioPlex
CTAGE5
Tbio
Novelty:  0.04516631
p_int:  0.975422683
p_ni:  0.024576881
p_wrong:  4.36e-7
Data Source:  BioPlex
HSPA5
Tchem
Novelty:  0.00043424
p_int:  0.972990561
p_ni:  0.027009439
Data Source:  BioPlex
MANBA
Tchem
Family:  Enzyme
Novelty:  0.00961026
p_int:  0.957732373
p_ni:  0.042267599
p_wrong:  2.8e-8
Data Source:  BioPlex
PPP2CA
Tchem
Family:  Enzyme
Novelty:  0.00496839
p_int:  0.95057357
p_ni:  0.04942643
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (6)
Collagen biosynthesis and modifying enzymes (R-HSA-1650814)

Click on a row in the table to change the structure displayed.

Find Similar Targets
Items per page:
1 – 4 of 4
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Collagen biosynthesis and modifying enzymes
Reactome
Collagen chain trimerization
Reactome
Collagen formation
Reactome
Extracellular matrix organization
Name
Explore in Pharos
Explore in Source
Collagen biosynthesis and modifying enzymes
Collagen chain trimerization
Collagen formation
Extracellular matrix organization
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (9)
Find Similar Targets
Items per page:
10
1 – 2 of 2
GO Term
Evidence
Assigned by
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Disease Associations (null)
No disease associations found
GWAS Traits (8)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
smoking cessation
2
3
5
92.4
cigarettes per day measurement
3
2
3
91.8
smoking behaviour measurement
1
1
1
78.3
2
2
2
77.8
smoking status measurement
2
1
2
70
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
smoking cessation
5
92.4
cigarettes per day measurement
3
91.8
smoking behaviour measurement
1
78.3
2
77.8
smoking status measurement
2
70
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (7)
1 – 5 of 7
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Mouse
MGI:1920618
73368
Rat
RGD:1563901
311716
Dog
collagen type XX alpha 1 chain
VGNC:39466
485971
Cow
collagen type XX alpha 1 chain
VGNC:27562
519501
Opossum
collagen type XX alpha 1 chain
100619266
Species
Name
OMA
EggNOG
Inparanoid
Mouse
Rat
Dog
collagen type XX alpha 1 chain
Cow
collagen type XX alpha 1 chain
Opossum
collagen type XX alpha 1 chain
Publication Statistics
PubMed Score 2.62
PubMed score by year
PubTator Score 11.64
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title