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Tbio
TAAR2
Trace amine-associated receptor 2

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IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 30.73   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 94   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 30.73   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 94   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Orthologs (10)
1 – 5 of 10
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
trace amine associated receptor 2, pseudogene
VGNC:12707
493904
Macaque
trace amine associated receptor 2
714074
Mouse
MGI:2685071
209512
Rat
RGD:1311240
294121
Horse
trace amine-associated receptor 2
100073123
Species
Name
OMA
EggNOG
Inparanoid
Chimp
trace amine associated receptor 2, pseudogene
Macaque
trace amine associated receptor 2
Mouse
Rat
Horse
trace amine-associated receptor 2
Pathways (9)
Amine ligand-binding receptors (R-HSA-375280)

Click on a row in the table to change the structure displayed.

Items per page:
1 – 5 of 7
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Amine ligand-binding receptors
Reactome
Class A/1 (Rhodopsin-like receptors)
Reactome
G alpha (s) signalling events
Reactome
GPCR downstream signalling
Reactome
GPCR ligand binding
Name
Explore in Pharos
Explore in Source
Amine ligand-binding receptors
Class A/1 (Rhodopsin-like receptors)
G alpha (s) signalling events
GPCR downstream signalling
GPCR ligand binding
Gene Ontology Terms (5)
Items per page:
10
1 – 2 of 2
GO Term
Evidence
Assigned by
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Traceable Author Statement (TAS)
ProtInc
Protein-Protein Interactions (132)
1 – 10 of 132
GCG
Tchem
Novelty: 0.00004879
Score: 0.927
Data Source: STRINGDB
SCT
Tbio
Novelty: 0.00070278
Score: 0.923
Data Source: STRINGDB
GPR15
Tbio
Family: GPCR
Novelty: 0.00673057
Score: 0.923
Data Source: STRINGDB
GPR39
Tchem
Family: GPCR
Novelty: 0.01244607
Score: 0.922
Data Source: STRINGDB
TAAR8
Tbio
Family: GPCR
Novelty: 0.00862757
Score: 0.919
Data Source: STRINGDB
GPR27
Tbio
Family: GPCR
Novelty: 0.164488
Score: 0.918
Data Source: STRINGDB
AVPR2
Tclin
Family: GPCR
Novelty: 0.0009139
Score: 0.918
Data Source: STRINGDB
GNB1
Tbio
Novelty: 0.02477955
Score: 0.916
Data Source: STRINGDB
GNB3
Tbio
Novelty: 0.0037117
Score: 0.916
Data Source: STRINGDB
SCTR
Tclin
Family: GPCR
Novelty: 0.01163942
Score: 0.916
Data Source: STRINGDB
Publication Statistics
PubMed Score  30.73

PubMed score by year
PubTator Score  16.32

PubTator score by year
Patents
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer