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Tbio
RAI14
Ankycorbin

Protein Summary
Description
Plays a role in actin regulation at the ectoplasmic specialization, a type of cell junction specific to testis. Important for establishment of sperm polarity and normal spermatid adhesion. May also promote integrity of Sertoli cell tight junctions at the blood-testis barrier.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000265109
  • ENSP00000265109
  • ENSG00000039560
  • ENST00000428746
  • ENSP00000388725
  • ENST00000503673
  • ENSP00000422942
  • ENST00000506376
  • ENSP00000423854
  • ENST00000512629
  • ENSP00000422377
  • ENST00000515799
  • ENSP00000427123

Symbol
  • KIAA1334
  • NORPEG
  • RAI13
  • NORPEG
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
kinase perturbation
0.93
PubMedID
0.86
transcription factor binding site profile
0.85
histone modification site profile
0.83
ligand (protein) perturbation
0.83


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 22.18   (req: < 5)
Gene RIFs: 3   (req: <= 3)
Antibodies: 69   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 22.18   (req: >= 5)
Gene RIFs: 3   (req: > 3)
Antibodies: 69   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (56)
VTN
Tbio
Family:  TF
Novelty:  0.00046861
p_int:  0.999998049
p_ni:  0.000001926
p_wrong:  2.5e-8
Data Source:  BioPlex
VAPB
Tbio
Novelty:  0.00542377
p_int:  0.999997148
p_ni:  0.000002851
p_wrong:  1e-9
Score:  0.182
Data Source:  BioPlex,STRINGDB
PSMC3
Tbio
Family:  Enzyme
Novelty:  0.04026019
p_int:  0.999995204
p_ni:  0.000004796
Score:  0.349
Data Source:  BioPlex,STRINGDB
PACSIN1
Tbio
Family:  Enzyme
Novelty:  0.01482925
p_int:  0.999972946
p_ni:  0.000027054
p_wrong:  1e-9
Score:  0.87
Data Source:  BioPlex,STRINGDB
PLK1
Tchem
Family:  Kinase
Novelty:  0.00062799
p_int:  0.999958487
p_ni:  0.000041512
Score:  0.323
Data Source:  BioPlex,STRINGDB
PARP16
Tchem
Family:  Enzyme
Novelty:  0.09651799
p_int:  0.999688757
p_ni:  0.000311243
Score:  0.204
Data Source:  BioPlex,STRINGDB
VAPA
Tbio
Novelty:  0.00169209
p_int:  0.99961064
p_ni:  0.00038936
Score:  0.179
Data Source:  BioPlex,STRINGDB
CAV3
Tbio
Novelty:  0.00190092
p_int:  0.998479736
p_ni:  0.001520259
p_wrong:  6e-9
Score:  0.167
Data Source:  BioPlex,STRINGDB
FURIN
Tchem
Family:  Enzyme
Novelty:  0.00055079
p_int:  0.987791131
p_ni:  0.012208869
Data Source:  BioPlex
BTRC
Tbio
Novelty:  0.00293475
p_int:  0.987526414
p_ni:  0.012473583
p_wrong:  3e-9
Score:  0.165
Data Source:  BioPlex,STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (8)
Find Similar Targets
Items per page:
10
1 – 6 of 6
GO Term
Evidence
Assigned by
Inferred from Direct Assay (IDA)
HPA
Inferred from Direct Assay (IDA)
HPA
Inferred from Direct Assay (IDA)
HPA
Inferred from Electronic Annotation (IEA)
UniProtKB-SubCell
Inferred from Electronic Annotation (IEA)
UniProtKB-SubCell
Inferred from Electronic Annotation (IEA)
UniProtKB-SubCell
Disease Associations ()
No disease associations found
GWAS Traits (9)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
urate measurement
2
2
2
86.6
hemoglobin measurement
2
2
2
81.8
red blood cell density measurement
1
1
1
70.5
hematocrit
1
1
1
67.7
reticulocyte measurement
2
1
2
54.4
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
urate measurement
2
86.6
hemoglobin measurement
2
81.8
red blood cell density measurement
1
70.5
hematocrit
1
67.7
reticulocyte measurement
2
54.4
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (14)
1 – 5 of 14
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
retinoic acid induced 14
VGNC:7116
461932
Macaque
retinoic acid induced 14
698620
Mouse
MGI:1922896
75646
Rat
RGD:1305942
294804
Dog
retinoic acid induced 14
VGNC:45329
479368
Species
Name
OMA
EggNOG
Inparanoid
Chimp
retinoic acid induced 14
Macaque
retinoic acid induced 14
Mouse
Rat
Dog
retinoic acid induced 14
Publication Statistics
PubMed Score 22.18
PubMed score by year
PubTator Score 6.09
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title