Tbio CWC15 Spliceosome-associated protein CWC15 homolog

Protein Summary

Description

Involved in pre-mRNA splicing as component of the spliceosome (PubMed:28502770, PubMed:28076346). Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing.

Uniprot Accession IDs

• Q9P013
• B2RC17
• Q05BV9
• Q05DM1
• Q9UI29

Gene Name

• CWC15

Ensembl ID

• ENST00000279839
• ENSP00000475615
• ENSG00000150316

Symbol

• C11orf5
• ORF5
• AD002
• Cwf15
• C11orf5
• HSPC148

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
interacting protein	0.93
histone modification site profile	0.89
tissue	0.68
tissue sample	0.66
transcription factor binding site profile	0.66

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 614.99   (req: < 5)

Gene RIFs: 1   (req: <= 3)

Antibodies: 69   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 614.99   (req: >= 5)

Gene RIFs: 1   (req: > 3)

Antibodies: 69   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0