Protein Summary
Odorant receptor. Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
- ENST00000322678
- ENSP00000323606
- ENSG00000179695
- ENST00000641202
- ENSP00000493222
- ENST00000641516
- ENSP00000493456
- OR6C67
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
cell type or tissue | 0.67 | ||
tissue | 0.66 | ||
cell line | 0.55 | ||
protein domain | 0.41 | ||
pathway | 0.31 | ||
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 32.48 (req: < 5)
Gene RIFs: 0 (req: <= 3)
Antibodies: 36 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 32.48 (req: >= 5)
Gene RIFs: 0 (req: > 3)
Antibodies: 36 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 3
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0
Pathways (7)
Reactome (5)
KEGG (1)
WikiPathways (1)
Click on a row in the table to change the structure displayed.
Items per page:
1 – 5 of 5
Data Source | Name | Explore in Pharos | Explore in Source | ||
|---|---|---|---|---|---|
Reactome | G alpha (s) signalling events | ||||
Reactome | GPCR downstream signalling | ||||
Reactome | Olfactory Signaling Pathway | ||||
Reactome | Signal Transduction | ||||
Reactome | Signaling by GPCR | ||||
Name | Explore in Pharos | Explore in Source | ||
|---|---|---|---|---|
G alpha (s) signalling events | ||||
GPCR downstream signalling | ||||
Olfactory Signaling Pathway | ||||
Signal Transduction | ||||
Signaling by GPCR | ||||
Gene Ontology Terms (5)
Functions (2)
Components (2)
Processes (1)
Items per page:
10
1 – 2 of 2
GO Term | Evidence | Assigned by | ||
|---|---|---|---|---|
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
Protein-Protein Interactions (30)
1 – 10 of 30
GNAL
Novelty: 0.0277957
Score: 0.911
Data Source: STRINGDB
GNGT1
Novelty: 0.03653174
Score: 0.901
Data Source: STRINGDB
RTP2
Novelty: 0.13129103
Score: 0.9
Data Source: STRINGDB
GNB1
Novelty: 0.04716243
Score: 0.9
Data Source: STRINGDB
REEP6
Novelty: 0.17493781
Score: 0.9
Data Source: STRINGDB
RTP1
Novelty: 0.04761905
Score: 0.9
Data Source: STRINGDB
REEP1
Novelty: 0.02999447
Score: 0.9
Data Source: STRINGDB
REEP4
Novelty: 0.34354551
Score: 0.9
Data Source: STRINGDB
RTP3
Novelty: 0.12230635
Score: 0.9
Data Source: STRINGDB
REEP5
Novelty: 0.00356586
Score: 0.9
Data Source: STRINGDB
Publication Statistics
PubMed Score 32.48
PubMed score by year
PubTator Score 26.45
PubTator score by year
Patents
Amino Acid Sequence
Residue Counts
Protein Sequence
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