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Tbio
GPRC5D
G-protein coupled receptor family C group 5 member D

Protein Summary
Description
The protein encoded by this gene is a member of the G protein-coupled receptor family; however, the specific function of this gene has not yet been determined. [provided by RefSeq, Jul 2008]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000228887
  • ENSP00000228887
  • ENSG00000111291
  • ENST00000396333
  • ENSP00000379624
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
tissue sample
0.65
cell type or tissue
0.61
cell line
0.47
pathway
0.45
disease perturbation
0.43


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 10.37   (req: < 5)
Gene RIFs: 3   (req: <= 3)
Antibodies: 191   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 10.37   (req: >= 5)
Gene RIFs: 3   (req: > 3)
Antibodies: 191   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Pathways (34)
Items per page:
1 – 5 of 34
Data Source
Name
Explore in Pharos
Explore in Source
WikiPathways
GPCRs, Class C Metabotropic glutamate, pheromone
WikiPathways
Amplification and Expansion of Oncogenic Pathways as Metastatic Traits
WikiPathways
Amplification and Expansion of Oncogenic Pathways as Metastatic Traits
WikiPathways
PI3K-AKT-mTOR signaling pathway and therapeutic opportunities
WikiPathways
Hair Follicle Development: Cytodifferentiation (Part 3 of 3)
Name
Explore in Pharos
Explore in Source
GPCRs, Class C Metabotropic glutamate, pheromone
Amplification and Expansion of Oncogenic Pathways as Metastatic Traits
Amplification and Expansion of Oncogenic Pathways as Metastatic Traits
PI3K-AKT-mTOR signaling pathway and therapeutic opportunities
Hair Follicle Development: Cytodifferentiation (Part 3 of 3)
Protein-Protein Interactions (22)
1 – 10 of 22
PRR9
Tdark
Novelty: 0.09345601
Score: 0.624
Data Source: STRINGDB
B4GALT4
Tbio
Family: Enzyme
Novelty: 0.11226614
Score: 0.611
Data Source: STRINGDB
GPR156
Tdark
Family: GPCR
Novelty: 0.39183023
Score: 0.596
Data Source: STRINGDB
SNHG28
Tdark
Novelty: 1.12069377
Score: 0.588
Data Source: STRINGDB
VSIG8
Tdark
Novelty: 1.16023405
Score: 0.582
Data Source: STRINGDB
GPR179
Tdark
Family: GPCR
Novelty: 0.09278403
Score: 0.56
Data Source: STRINGDB
VSTM4
Tdark
Novelty: 0.46711608
Score: 0.543
Data Source: STRINGDB
SEC63
Tbio
Novelty: 0.00974614
Score: 0.534
Data Source: STRINGDB
LRRC15
Tbio
Novelty: 0.03701624
Score: 0.527
Data Source: STRINGDB
GPBAR1
Tchem
Family: GPCR
Novelty: 0.00290465
Score: 0.474
Data Source: STRINGDB
Publication Statistics
PubMed Score  10.37

PubMed score by year
PubTator Score  11.77

PubTator score by year
Patents
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer