Tbio USE1 Vesicle transport protein USE1

Protein Summary

Description

SNARE that may be involved in targeting and fusion of Golgi-derived retrograde transport vesicles with the ER.

Uniprot Accession IDs

• Q9NZ43
• Q8NCK1
• Q9BRT4

Gene Name

• USE1

Ensembl ID

• ENST00000263897
• ENSP00000263897
• ENSG00000053501
• ENST00000595101
• ENSP00000472362
• ENST00000596136
• ENSP00000473239

Symbol

• USE1L
• D12
• P31
• SLT1
• MDS032

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
histone modification site profile	0.93
disease perturbation	0.87
interacting protein	0.85
transcription factor binding site profile	0.84
transcription factor perturbation	0.84

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 154.05   (req: < 5)

Gene RIFs: 7   (req: <= 3)

Antibodies: 205   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 154.05   (req: >= 5)

Gene RIFs: 7   (req: > 3)

Antibodies: 205   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0