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Tbio
ACTR10
Actin-related protein 10

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000254286
  • ENSP00000254286
  • ENSG00000131966

Symbol
  • ACTR11
  • ARP11
  • Arp10
  • Arp11
  • ACTR11
  • HARP11
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
disease perturbation
0.99
kinase perturbation
0.97
virus perturbation
0.94
histone modification site profile
0.92
tissue sample
0.58


Related Tools
Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 8.67   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 84   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 8.67   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 84   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (2)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
alcohol consumption measurement
1
1
1
53.3
reticulocyte measurement
2
1
2
17.5
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
alcohol consumption measurement
1
53.3
reticulocyte measurement
2
17.5
Orthologs (15)
1 – 5 of 15
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
actin related protein 10 homolog
452933
Macaque
actin related protein 10 homolog
700125
Mouse
MGI:1891654
56444
Rat
RGD:1306515
299121
Dog
actin related protein 10 homolog
VGNC:37551
480337
Species
Name
OMA
EggNOG
Inparanoid
Chimp
actin related protein 10 homolog
Macaque
actin related protein 10 homolog
Mouse
Rat
Dog
actin related protein 10 homolog
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q9NZ32-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Pathways (20)
Adaptive Immune System (R-HSA-1280218)

Click on a row in the table to change the structure displayed.

Items per page:
1 – 5 of 19
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Adaptive Immune System
Reactome
Asparagine N-linked glycosylation
Reactome
COPI-independent Golgi-to-ER retrograde traffic
Reactome
COPI-mediated anterograde transport
Reactome
Cellular responses to external stimuli
Name
Explore in Pharos
Explore in Source
Adaptive Immune System
Asparagine N-linked glycosylation
COPI-independent Golgi-to-ER retrograde traffic
COPI-mediated anterograde transport
Cellular responses to external stimuli
Protein-Protein Interactions (347)
1 – 10 of 347
DCTN5
Tdark
Novelty: 0.19530162
p_int: 0.999999165
p_ni: 8.35e-7
Score: 0.985
Data Source: BioPlex,Reactome,STRINGDB
DCTN6
Tdark
Novelty: 0.30624393
p_int: 0.999999089
p_ni: 9.1e-7
p_wrong: 1e-9
Score: 0.998
Data Source: BioPlex,Reactome,STRINGDB
DCTN2
Tbio
Novelty: 0.01045432
p_int: 0.999998333
p_ni: 0.000001666
p_wrong: 2e-9
Score: 0.998
Data Source: BioPlex,Reactome,STRINGDB
DCTN1
Tbio
Novelty: 0.00494896
p_int: 0.999997074
p_ni: 0.000002925
p_wrong: 1e-9
Score: 0.997
Data Source: BioPlex,Reactome,STRINGDB
CAPZA2
Tbio
Novelty: 0.14014918
p_int: 0.999990406
p_ni: 0.000009594
Score: 0.966
Data Source: BioPlex,Reactome,STRINGDB
ACTR1A
Tbio
Novelty: 0.06306209
p_int: 0.999980666
p_ni: 0.000019334
Score: 0.996
Data Source: BioPlex,Reactome,STRINGDB
KLHL2
Tbio
Novelty: 0.07279226
p_int: 0.999979619
p_ni: 0.000020377
p_wrong: 4e-9
Score: 0.252
Data Source: BioPlex,STRINGDB
ACTR1B
Tbio
Novelty: 0.10014723
p_int: 0.999965876
p_ni: 0.000034124
Score: 0.995
Data Source: BioPlex,STRINGDB
DEFB127
Tbio
Novelty: 0.18126756
p_int: 0.999326072
p_ni: 0.000673928
Score: 0.691
Data Source: BioPlex,STRINGDB
UQCRH
Tbio
Novelty: 0.04494433
p_int: 0.996619836
p_ni: 0.003380048
p_wrong: 1.16e-7
Score: 0.484
Data Source: BioPlex,STRINGDB
Publication Statistics
PubMed Score  8.67

PubMed score by year
PubTator Score  0.11

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer