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Tbio
BET1L
BET1-like protein

Protein Summary
Description
Vesicle SNARE required for targeting and fusion of retrograde transport vesicles with the Golgi complex. Required for the integrity of the Golgi complex (By similarity).
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000382762
  • ENSP00000372210
  • ENSG00000177951

Symbol
  • GS15
  • GS15
  • BET1L1
  • GOLIM3
  • HSPC197
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor perturbation
0.8
cellular component
0.73
kinase perturbation
0.71
histone modification site profile
0.69
transcription factor binding site profile
0.69


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.42   (req: < 5)
Gene RIFs: 4   (req: <= 3)
Antibodies: 35   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.42   (req: >= 5)
Gene RIFs: 4   (req: > 3)
Antibodies: 35   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (202)
VAMP5
Tbio
Novelty:  0.09958312
p_int:  0.998154678
p_ni:  5.43e-7
p_wrong:  0.001844779
Score:  0.743
Data Source:  BioPlex,STRINGDB
STX18
Tbio
Novelty:  0.0259034
p_int:  0.862187206
p_ni:  0.000014843
p_wrong:  0.137797951
Score:  0.831
Data Source:  BioPlex,STRINGDB
YKT6
Tbio
Novelty:  0.01591063
Score:  0.992
Data Source:  Reactome,STRINGDB
STX5
Tbio
Novelty:  0.00964918
Score:  0.991
Data Source:  Reactome,STRINGDB
GOSR1
Tbio
Novelty:  0.03139481
Score:  0.991
Data Source:  Reactome,STRINGDB
GOSR2
Tbio
Novelty:  0.02447711
Score:  0.99
Data Source:  STRINGDB
USO1
Tbio
Novelty:  0.02066669
Score:  0.987
Data Source:  STRINGDB
GOLGA2
Tbio
Novelty:  0.00544771
Score:  0.963
Data Source:  STRINGDB
NSF
Tbio
Family:  Enzyme
Novelty:  0.00173489
Score:  0.95
Data Source:  Reactome,STRINGDB
SEC22B
Tbio
Novelty:  0.03035448
Score:  0.948
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (11)
Asparagine N-linked glycosylation (R-HSA-446203)

Click on a row in the table to change the structure displayed.

Find Similar Targets
Items per page:
1 – 5 of 10
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Asparagine N-linked glycosylation
Reactome
COPI-mediated anterograde transport
Reactome
ER to Golgi Anterograde Transport
Reactome
Intra-Golgi and retrograde Golgi-to-ER traffic
Reactome
Intra-Golgi traffic
Name
Explore in Pharos
Explore in Source
Asparagine N-linked glycosylation
COPI-mediated anterograde transport
ER to Golgi Anterograde Transport
Intra-Golgi and retrograde Golgi-to-ER traffic
Intra-Golgi traffic
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (35)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
mean platelet volume
6
6
9
99.4
platelet count
5
4
3
4.7
98.4
alkaline phosphatase measurement
3
3
3
17.9
96.7
mean corpuscular volume
3
3
3
92.1
5
5
0
1.2
91.4
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
mean platelet volume
9
99.4
platelet count
3
4.7
98.4
alkaline phosphatase measurement
3
17.9
96.7
mean corpuscular volume
3
92.1
0
1.2
91.4
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (12)
1 – 5 of 12
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
Bet1 golgi vesicular membrane trafficking protein like
VGNC:6761
450910
Macaque
Bet1 golgi vesicular membrane trafficking protein like
696599
Mouse
MGI:1913128
54399
Rat
RGD:71051
54400
Dog
Bet1 golgi vesicular membrane trafficking protein like
VGNC:38438
483393
Species
Name
OMA
EggNOG
Inparanoid
Chimp
Bet1 golgi vesicular membrane trafficking protein like
Macaque
Bet1 golgi vesicular membrane trafficking protein like
Mouse
Rat
Dog
Bet1 golgi vesicular membrane trafficking protein like
Publication Statistics
PubMed Score 4.42
PubMed score by year
PubTator Score 12.56
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title