Protein Classes
Protein Summary
Vesicle SNARE required for targeting and fusion of retrograde transport vesicles with the Golgi complex. Required for the integrity of the Golgi complex (By similarity).
- ENST00000382762
- ENSP00000372210
- ENSG00000177951
- GS15
- GS15
- BET1L1
- GOLIM3
- HSPC197
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
transcription factor perturbation | 0.8 | ||
cellular component | 0.73 | ||
kinase perturbation | 0.71 | ||
histone modification site profile | 0.69 | ||
transcription factor binding site profile | 0.69 | ||
Related Tools
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 3.92 (req: < 5)
Gene RIFs: 4 (req: <= 3)
Antibodies: 35 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 3.92 (req: >= 5)
Gene RIFs: 4 (req: > 3)
Antibodies: 35 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 5
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0
GWAS Traits (16)
Items per page:
1 – 5 of 16
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
|---|---|---|---|---|---|---|---|---|---|
mean platelet volume | 4 | 4 | 7 | 97.1 | |||||
platelet count | 4 | 3 | 3 | 5.3 | 96.2 | ||||
2 | 2 | 0 | 1.3 | 91.1 | |||||
red blood cell distribution width | 3 | 1 | 3 | 84.2 | |||||
mean corpuscular hemoglobin concentration | 2 | 2 | 2 | 76.1 | |||||
Items per page:
1 – 5 of 16
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
|---|---|---|---|---|---|---|---|
mean platelet volume | 7 | 97.1 | |||||
platelet count | 3 | 5.3 | 96.2 | ||||
0 | 1.3 | 91.1 | |||||
red blood cell distribution width | 3 | 84.2 | |||||
mean corpuscular hemoglobin concentration | 2 | 76.1 | |||||
Orthologs (12)
1 – 5 of 12
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
|---|---|---|---|---|---|---|---|---|
Chimp | Bet1 golgi vesicular membrane trafficking protein like | VGNC:6761 | 450910 | |||||
Macaque | Bet1 golgi vesicular membrane trafficking protein like | 696599 | ||||||
Mouse | MGI:1913128 | 54399 | ||||||
Rat | RGD:71051 | 54400 | ||||||
Dog | Bet1 golgi vesicular membrane trafficking protein like | VGNC:38438 | 483393 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
|---|---|---|---|---|---|---|
Chimp | Bet1 golgi vesicular membrane trafficking protein like | |||||
Macaque | Bet1 golgi vesicular membrane trafficking protein like | |||||
Mouse | ||||||
Rat | ||||||
Dog | Bet1 golgi vesicular membrane trafficking protein like | |||||
Protein Structure (0 Structures, 1 AlphaFold Model)
Pathways (11)
Reactome (10)
KEGG (1)
Click on a row in the table to change the structure displayed.
Items per page:
1 – 5 of 10
Data Source | Name | Explore in Pharos | Explore in Source | ||
|---|---|---|---|---|---|
Reactome | Asparagine N-linked glycosylation | ||||
Reactome | COPI-mediated anterograde transport | ||||
Reactome | ER to Golgi Anterograde Transport | ||||
Reactome | Intra-Golgi and retrograde Golgi-to-ER traffic | ||||
Reactome | Intra-Golgi traffic | ||||
Name | Explore in Pharos | Explore in Source | ||
|---|---|---|---|---|
Asparagine N-linked glycosylation | ||||
COPI-mediated anterograde transport | ||||
ER to Golgi Anterograde Transport | ||||
Intra-Golgi and retrograde Golgi-to-ER traffic | ||||
Intra-Golgi traffic | ||||
Gene Ontology Terms (12)
Functions (1)
Components (7)
Processes (4)
Items per page:
10
1 – 1 of 1
GO Term | Evidence | Assigned by | ||
|---|---|---|---|---|
Inferred from Direct Assay (IDA) | HGNC | |||
Protein-Protein Interactions (202)
1 – 10 of 202
VAMP5
Novelty: 0.09958312
p_int: 0.998154678
p_ni: 5.43e-7
p_wrong: 0.001844779
Score: 0.743
Data Source: BioPlex,STRINGDB
STX18
Novelty: 0.0259034
p_int: 0.862187206
p_ni: 0.000014843
p_wrong: 0.137797951
Score: 0.831
Data Source: BioPlex,STRINGDB
YKT6
Novelty: 0.01591063
Score: 0.992
Data Source: Reactome,STRINGDB
STX5
Novelty: 0.00964918
Score: 0.991
Data Source: Reactome,STRINGDB
GOSR1
Novelty: 0.03139481
Score: 0.991
Data Source: Reactome,STRINGDB
GOSR2
Novelty: 0.02447711
Score: 0.99
Data Source: STRINGDB
USO1
Novelty: 0.02066669
Score: 0.987
Data Source: STRINGDB
GOLGA2
Novelty: 0.00544771
Score: 0.963
Data Source: STRINGDB
NSF
Family: Enzyme
Novelty: 0.00173489
Score: 0.95
Data Source: Reactome,STRINGDB
SEC22B
Novelty: 0.03035448
Score: 0.948
Data Source: STRINGDB
Publication Statistics
PubMed Score 3.92
PubMed score by year
PubTator Score 12.56
PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer
Find similar targets by:
UniProt Keyword