Tbio GPR83 Probable G-protein coupled receptor 83

Protein Summary

Description

Orphan receptor. Could be a neuropeptide Y receptor.

Uniprot Accession IDs

• Q9NYM4
• B0M0K5
• Q6NWR4
• Q9P1Y8

Gene Name

• GPR83

Ensembl ID

• ENST00000243673
• ENSP00000243673
• ENSG00000123901

Symbol

• GPR72
• KIAA1540
• GIR
• GPR72

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
cell line	0.7
histone modification site profile	0.6
microRNA	0.6
PubMedID	0.59
gene perturbation	0.57

Protein Classes

DTO Classes

Protein / G-protein Coupled Receptor / Class A Rhodopsin Like / Probable G-protein Coupled Receptor 83

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 52.4   (req: < 5)

Gene RIFs: 3   (req: <= 3)

Antibodies: 363   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 52.4   (req: >= 5)

Gene RIFs: 3   (req: > 3)

Antibodies: 363   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 1

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0