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Tbio
COA4
Cytochrome c oxidase assembly factor 4 homolog, mitochondrial

Protein Summary
Description
Putative COX assembly factor.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000355693
  • ENSP00000347919
  • ENSG00000181924
  • ENST00000537289
  • ENSP00000437772
  • ENST00000541455
  • ENSP00000440756
  • ENST00000545127
  • ENSP00000443795

Symbol
  • CHCHD8
  • E2IG2
  • CMC3
  • E2IG2
  • CHCHD8
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.93
cell type or tissue
0.76
kinase perturbation
0.71
tissue
0.67
transcription factor binding site profile
0.67


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 9.61   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 93   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 9.61   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 93   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (29)
CHCHD4
Tbio
Novelty:  0.01204944
Score:  0.967
Data Source:  STRINGDB
GFER
Tchem
Family:  Enzyme
Novelty:  0.00338563
Score:  0.941
Data Source:  STRINGDB
TIMM22
Tbio
Family:  Enzyme
Novelty:  0.12627933
Score:  0.923
Data Source:  STRINGDB
CYC1
Tchem
Novelty:  0.01369865
Score:  0.916
Data Source:  STRINGDB
ATP5MC1
Tbio
Family:  Enzyme
Novelty:  0.03538978
Score:  0.908
Data Source:  STRINGDB
BCS1L
Tbio
Family:  Enzyme
Novelty:  0.01764582
Score:  0.903
Data Source:  STRINGDB
HSPD1
Tbio
Novelty:  0.00018924
Score:  0.903
Data Source:  STRINGDB
HSPA9
Tchem
Novelty:  0.00235171
Score:  0.9
Data Source:  STRINGDB
SLC25A4
Tbio
Family:  Transporter
Novelty:  0.01250865
Score:  0.9
Data Source:  STRINGDB
ATP5F1A
Tbio
Family:  Enzyme
Novelty:  0.01052213
Score:  0.9
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (3)
Mitochondrial protein import (R-HSA-1268020)

Click on a row in the table to change the structure displayed.

Find Similar Targets
Items per page:
1 – 2 of 2
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Mitochondrial protein import
Reactome
Protein localization
Name
Explore in Pharos
Explore in Source
Mitochondrial protein import
Protein localization
Viral Interactions (0)
No viral interactions found
Disease Associations ()
No disease associations found
GWAS Traits (0)
No GWAS traits found
IDG Resources
No IDG generated resources found
Orthologs (10)
1 – 5 of 10
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Macaque
coiled-coil-helix-coiled-coil-helix domain containing 8
718275
Mouse
MGI:1915435
68185
Rat
RGD:1562228
499214
Horse
cytochrome c oxidase assembly factor 4 homolog
VGNC:16707
100629588
Pig
cytochrome c oxidase assembly factor 4 homolog, mitochondrial
100514530
Species
Name
OMA
EggNOG
Inparanoid
Macaque
coiled-coil-helix-coiled-coil-helix domain containing 8
Mouse
Rat
Horse
cytochrome c oxidase assembly factor 4 homolog
Pig
cytochrome c oxidase assembly factor 4 homolog, mitochondrial
Publication Statistics
PubMed Score 9.61
PubMed score by year
PubTator Score 10.83
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title