ANAPC11
Anaphase-promoting complex subunit 11
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
biological process | 0.94 | ||
virus perturbation | 0.92 | ||
histone modification site profile | 0.8 | ||
disease perturbation | 0.74 | ||
cell type or tissue | 0.68 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | APC-Cdc20 mediated degradation of Nek2A | ||||
Reactome | APC/C-mediated degradation of cell cycle proteins | ||||
Reactome | APC/C:Cdc20 mediated degradation of Cyclin B | ||||
Reactome | APC/C:Cdc20 mediated degradation of Securin | ||||
Reactome | APC/C:Cdc20 mediated degradation of mitotic proteins | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
APC-Cdc20 mediated degradation of Nek2A | ||||
APC/C-mediated degradation of cell cycle proteins | ||||
APC/C:Cdc20 mediated degradation of Cyclin B | ||||
APC/C:Cdc20 mediated degradation of Securin | ||||
APC/C:Cdc20 mediated degradation of mitotic proteins | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | MGI | |||
Inferred from Direct Assay (IDA) | MGI | |||
Inferred from Direct Assay (IDA) | MGI | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
vital capacity | 1 | 1 | 1 | 73.2 | |||||
BMI-adjusted waist-hip ratio | 2 | 3 | 3 | 58.3 | |||||
hematocrit | 2 | 2 | 2 | 55.2 | |||||
hemoglobin measurement | 1 | 1 | 1 | 47.7 | |||||
forced expiratory volume | 1 | 1 | 1 | 46.5 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
vital capacity | 1 | 73.2 | |||||
BMI-adjusted waist-hip ratio | 3 | 58.3 | |||||
hematocrit | 2 | 55.2 | |||||
hemoglobin measurement | 1 | 47.7 | |||||
forced expiratory volume | 1 | 46.5 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | anaphase promoting complex subunit 11 | VGNC:6334 | 454972 | |||||
Macaque | anaphase promoting complex subunit 11 | 714909 | ||||||
Mouse | MGI:1913406 | 66156 | ||||||
Dog | anaphase promoting complex subunit 11 | VGNC:51919 | 483370 | |||||
Cow | anaphase promoting complex subunit 11 | 616275 | ||||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | anaphase promoting complex subunit 11 | |||||
Macaque | anaphase promoting complex subunit 11 | |||||
Mouse | ||||||
Dog | anaphase promoting complex subunit 11 | |||||
Cow | anaphase promoting complex subunit 11 | |||||
PMID | Year | Title |
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