MTMR4
Myotubularin-related protein 4
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
protein domain | 0.97 | ||
transcription factor binding site profile | 0.94 | ||
disease perturbation | 0.93 | ||
transcription factor perturbation | 0.8 | ||
pathway | 0.78 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Downregulation of TGF-beta receptor signaling | ||||
Reactome | Metabolism | ||||
Reactome | Metabolism of lipids | ||||
Reactome | PI Metabolism | ||||
Reactome | Phospholipid metabolism | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Downregulation of TGF-beta receptor signaling | ||||
Metabolism | ||||
Metabolism of lipids | ||||
PI Metabolism | ||||
Phospholipid metabolism | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Physical Interaction (IPI) | UniProtKB | |||
Traceable Author Statement (TAS) | Reactome | |||
Traceable Author Statement (TAS) | Reactome | |||
Traceable Author Statement (TAS) | Reactome | |||
Traceable Author Statement (TAS) | ProtInc | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
2 | 1 | 0 | 1.3 | 72.6 | |||||
intelligence | 3 | 2 | 1 | 6.5 | 60.1 | ||||
2 | 1 | 0 | 1.2 | 57.3 | |||||
C-reactive protein measurement | 1 | 1 | 1 | 46.9 | |||||
cognitive function measurement | 2 | 2 | 2 | 45.6 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
0 | 1.3 | 72.6 | |||||
intelligence | 1 | 6.5 | 60.1 | ||||
0 | 1.2 | 57.3 | |||||
C-reactive protein measurement | 1 | 46.9 | |||||
cognitive function measurement | 2 | 45.6 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | myotubularin related protein 4 | VGNC:9465 | 455157 | |||||
Mouse | MGI:2180699 | 170749 | ||||||
Rat | RGD:1310306 | 287607 | ||||||
Dog | myotubularin related protein 4 | VGNC:43485 | 480570 | |||||
Horse | myotubularin related protein 4 | VGNC:20427 | 100070938 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | myotubularin related protein 4 | |||||
Mouse | ||||||
Rat | ||||||
Dog | myotubularin related protein 4 | |||||
Horse | myotubularin related protein 4 | |||||
PMID | Year | Title |
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