Tbio BARHL2 BarH-like 2 homeobox protein

Protein Summary

Description

Potential regulator of neural basic helix-loop-helix genes.

Uniprot Accession IDs

• Q9NY43
• A0AVP2
• Q7Z4N7

Gene Name

• BARHL2

Ensembl ID

• ENST00000370445
• ENSP00000359474
• ENSG00000143032

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
biological process	0.74
gene perturbation	0.68
transcription factor	0.63
protein domain	0.58
PubMedID	0.56

Protein Classes

PANTHER Classes

Protein / Transcription Factor / Helix-turn-helix Transcription Factor / Homeodomain Transcription Factor / Barh-like 2 Homeobox Protein

Protein / Nucleic Acid Binding / Dna Binding Protein / Barh-like 2 Homeobox Protein

DTO Classes

Protein / Transcription Factor / Helix-turn-helix Transcription Factor / Homeodomain Transcription Factor / Barh-like 2 Homeobox Protein

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 13.02   (req: < 5)

Gene RIFs: 0   (req: <= 3)

Antibodies: 70   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 13.02   (req: >= 5)

Gene RIFs: 0   (req: > 3)

Antibodies: 70   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 13

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0