Tbio BTG4 Protein BTG4

Protein Summary

Description

Shows marked antiproliferative activity, being able to induce G(1) arrest. The protein encoded by this gene is a member of the BTG/Tob family. This family has structurally related proteins that appear to have antiproliferative properties. This encoded protein can induce G1 arrest in the cell cycle. [provided by RefSeq, Jul 2008]

Uniprot Accession IDs

• Q9NY30
• Q8NEH7

Gene Name

• BTG4

Ensembl ID

• ENST00000356018
• ENSP00000348300
• ENSG00000137707
• ENST00000525791
• ENSP00000432018

Symbol

• PC3B
• PC3B
• APRO3

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
gene perturbation	0.67
tissue sample	0.53
cell line	0.44
chemical	0.41
histone modification site profile	0.39

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 32.39   (req: < 5)

Gene RIFs: 8   (req: <= 3)

Antibodies: 139   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 32.39   (req: >= 5)

Gene RIFs: 8   (req: > 3)

Antibodies: 139   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0