Tdark CWC25 Pre-mRNA-splicing factor CWC25 homolog

Protein Summary

Description

This gene encodes a factor that is part of the multi-protein C complex involved in pre-mRNA splicing. Alternatively spliced transcripts have been described for this gene. [provided by RefSeq, Nov 2012]

Uniprot Accession IDs

• Q9NXE8
• A0JLM3
• Q68DK5

Gene Name

• CWC25

Ensembl ID

• ENST00000614790
• ENSP00000478070
• ENSG00000273559
• ENST00000614868
• ENSP00000477799
• ENSG00000276761

Symbol

• CCDC49
• CCDC49

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
virus perturbation	1
histone modification site profile	0.9
transcription factor	0.67
transcription factor binding site profile	0.67
cell line	0.63

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 9.93   (req: < 5)

Gene RIFs: 0   (req: <= 3)

Antibodies: 23   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 9.93   (req: >= 5)

Gene RIFs: 0   (req: > 3)

Antibodies: 23   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0