You are using an outdated browser. Please upgrade your browser to improve your experience.

Tdark
TMEM260
Transmembrane protein 260

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000261556
  • ENSP00000261556
  • ENSG00000070269
  • ENST00000538838
  • ENSP00000441934

Symbol
  • C14orf101
  • SHDRA
  • C14orf101
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
microRNA
0.88
transcription factor binding site profile
0.81
transcription factor perturbation
0.74
cell type or tissue
0.7
histone modification site profile
0.68


Related Tools
Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.15   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 46   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.15   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 46   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (1)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
hip bone size
1
1
1
59.9
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
hip bone size
1
59.9
Orthologs (10)
1 – 5 of 10
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
transmembrane protein 260
VGNC:3302
467464
Mouse
MGI:2443219
218989
Rat
RGD:1562018
361030
Dog
transmembrane protein 260
VGNC:47563
490707
Horse
transmembrane protein 260
VGNC:24278
100057780
Species
Name
OMA
EggNOG
Inparanoid
Chimp
transmembrane protein 260
Mouse
Rat
Dog
transmembrane protein 260
Horse
transmembrane protein 260
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q9NX78-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Gene Ontology Terms (1)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Protein-Protein Interactions (11)
1 – 10 of 11
CYP2C18
Tchem
Novelty: 0.00210821
p_int: 0.999999708
p_ni: 2.2e-8
p_wrong: 2.7e-7
Score: 0.269
Data Source: BioPlex,STRINGDB
MYH1
Tbio
Novelty: 0.00472973
p_int: 0.999968323
p_ni: 0.00003043
p_wrong: 0.000001247
Score: 0.309
Data Source: BioPlex,STRINGDB
MYH3
Tbio
Novelty: 0.00544794
p_int: 0.999955511
p_ni: 0.000044376
p_wrong: 1.13e-7
Score: 0.345
Data Source: BioPlex,STRINGDB
MYH4
Tbio
Novelty: 0.00556982
p_int: 0.999940316
p_ni: 0.000059684
Score: 0.239
Data Source: BioPlex,STRINGDB
MYLK2
Tchem
Family: Kinase
Novelty: 0.0080273
p_int: 0.999835411
p_ni: 0.000164578
p_wrong: 1e-8
Score: 0.345
Data Source: BioPlex,STRINGDB
MYH7
Tbio
Novelty: 0.00268092
p_int: 0.999744732
p_ni: 0.000255266
p_wrong: 2e-9
Score: 0.228
Data Source: BioPlex,STRINGDB
TOGARAM1
Tdark
Novelty: 0.23837453
Score: 0.587
Data Source: STRINGDB
MYL1
Tbio
Novelty: 0.00360262
Score: 0.507
Data Source: STRINGDB
DDHD1
Tbio
Family: Enzyme
Novelty: 0.05209502
Score: 0.478
Data Source: STRINGDB
GOLGA7
Tbio
Novelty: 0.17108842
Score: 0.448
Data Source: STRINGDB
Publication Statistics
PubMed Score  3.15

PubMed score by year
PubTator Score  1.53

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer
Find similar targets by: